ID U3JHS7_FICAL Unreviewed; 687 AA.
AC U3JHS7;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=NHL repeat containing 2 {ECO:0000313|Ensembl:ENSFALP00000002331.1};
GN Name=NHLRC2 {ECO:0000313|Ensembl:ENSFALP00000002331.1};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000002331.1, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000002331.1, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000002331.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; U3JHS7; -.
DR STRING; 59894.ENSFALP00000002331; -.
DR Ensembl; ENSFALT00000002343.2; ENSFALP00000002331.1; ENSFALG00000002241.2.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00390000015483; -.
DR HOGENOM; CLU_013730_0_0_1; -.
DR OMA; IAMAGVH; -.
DR Proteomes; UP000016665; Chromosome 6.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR CDD; cd14951; NHL-2_like; 1.
DR CDD; cd03012; TlpA_like_DipZ_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR045302; NHL2_NHL_rpt_dom.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01436; NHL; 3.
DR Pfam; PF13905; Thioredoxin_8; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51125; NHL; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..200
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REPEAT 475..518
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
SQ SEQUENCE 687 AA; 74591 MW; AD0F06C6212222D0 CRC64;
MDSRERDLTV PELGGDLQWL NTEGPISLHK DLCGKVVVLD FFTYCCINCL HLLPDLHALE
HQYSDKDGLV IVGVHSAKFP NEKVLDNIKS AVLRYNIVHP VVNDADATLW HELEVSCWPT
LVILGPRGNM LFSLVGEGHR EKLFLFTSIT LKFYKEKGQI KDNNIGIKLY RDSLPPSPLL
FPGKVTVDDS GERLVIADTG HHRILVTRKN GQILHTIGGP NSGRRDGGFS EAAFNSPQGI
AIKNNVIYVA DTENHLIRKI DLELQMVTTV AGIGVQGVDK EGGAKGEEQP ISSPWDVVFG
SSVSGTQEDD VLWIAMAGIH QIWALMLEGG KLPKGSDLKK GVCLRFAGSG NEENRNNAYP
HKAGFAQPSG LSLAPEEPWS CLFVADSESS TVRSISLKDG AVKHLVGGER DPLNLFAFGD
VDGAGINAKL QHPLGVTWDK KRKLLYVADS YNHKIKVVDP KMKNCATLAG TGEAGNVVGS
SFTQSAFNEP GGLCVEENGR LMYVADTNNH QIKVLDLETK ILSMLPILKP EACDVPDNLP
VQKDKIANLP RLPKSAPNIQ LPSLIVAPGQ TIQFLLKLTL PPDSKLNEEA PSAWFITAED
NTWLLQGQCL TGEIKDVPCQ TVIPFQLPGS CVSAEATLAI KACLYYCSKG SSACMMAGIS
FSQPLQVTGT DQGSSAQVEL IHTFVTN
//
