ID   U3JJQ8_FICAL            Unreviewed;       885 AA.
AC   U3JJQ8;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=Sorting nexin 14 {ECO:0000313|Ensembl:ENSFALP00000003012.2};
GN   Name=SNX14 {ECO:0000313|Ensembl:ENSFALP00000003012.2};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000003012.2, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000003012.2, ECO:0000313|Proteomes:UP000016665}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23103876; DOI=10.1038/nature11584;
RA   Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA   Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA   Wolf J.B.;
RT   "The genomic landscape of species divergence in Ficedula flycatchers.";
RL   Nature 491:756-760(2012).
RN   [2] {ECO:0000313|Ensembl:ENSFALP00000003012.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   RefSeq; XP_016152972.1; XM_016297486.1.
DR   AlphaFoldDB; U3JJQ8; -.
DR   STRING; 59894.ENSFALP00000003012; -.
DR   Ensembl; ENSFALT00000003025.2; ENSFALP00000003012.2; ENSFALG00000002867.2.
DR   GeneID; 101818974; -.
DR   CTD; 57231; -.
DR   eggNOG; KOG2101; Eukaryota.
DR   GeneTree; ENSGT00950000182856; -.
DR   Proteomes; UP000016665; Chromosome 3.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:InterPro.
DR   CDD; cd06877; PX_SNX14; 1.
DR   CDD; cd08722; RGS_SNX14; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR   InterPro; IPR003114; Phox_assoc.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR016137; RGS.
DR   InterPro; IPR036305; RGS_sf.
DR   InterPro; IPR044926; RGS_subdomain_2.
DR   InterPro; IPR037436; SNX14_PX.
DR   InterPro; IPR037892; SNX14_RGS.
DR   InterPro; IPR013937; Sorting_nexin_C.
DR   PANTHER; PTHR22775; SORTING NEXIN; 1.
DR   PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR   Pfam; PF08628; Nexin_C; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF02194; PXA; 1.
DR   Pfam; PF00615; RGS; 1.
DR   SMART; SM00312; PX; 1.
DR   SMART; SM00313; PXA; 1.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR   PROSITE; PS50195; PX; 1.
DR   PROSITE; PS51207; PXA; 1.
DR   PROSITE; PS50132; RGS; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT   DOMAIN          78..252
FT                   /note="PXA"
FT                   /evidence="ECO:0000259|PROSITE:PS51207"
FT   DOMAIN          284..416
FT                   /note="RGS"
FT                   /evidence="ECO:0000259|PROSITE:PS50132"
FT   DOMAIN          509..629
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
SQ   SEQUENCE   885 AA;  103053 MW;  7D8EA297AE7F6E65 CRC64;
     MIFWSFVAGV VTFYCSLGPD SLLPNILFTI KYKPKQLELP ELFPQGHSCA VCGKVKCKRH
     RPTLLLENYQ PWLDLKVPSK VDASLSEVLE LVLENFIYPW YRNITDDESS VDELRGTLRF
     FASVLVRRIH KVDIPTVVTK KMLKAAMKHI EVIAKARQKV KNAEFLQQAA LEEYGPELHV
     ALRSRRDELH YLRKLTELLF PYILPPKSTE CRSLALLIRE ILPGSVFLPS MDFLADPDTV
     NHLLLIFIDD SPPEIATEPT SSLVPFLQKF AEPRNKKPSV LKLELKEIRD QQDLLFRFMN
     FLKQEGAVHV LQFCLTVEEF NDRILRPELS DTEKMSLHDE VQKIYKTYCL DESIDKIRFD
     PFIVEEIQRI AEGPYMDVVK LQTMRCLFEA YEHVLSLLEN VFTPMFCHSD EYFRHLLRGA
     ESPTRNSKFN RTTQKRGESF GISKIGNKIK GVFKSSAMEG AMLPNYNLNE GEDDFIEEGV
     MVMEDDSPEE AVTTPNTPRN LAAWKISIPY VDFFDDPSLE RKDRKERIPV FCIDVERNDR
     KAVGHEPEHW SVYRRYLEFY VLESKLTEFH GTFPDAQLPS KRIIGPKNYE FLKSKREEFQ
     EYLQKLLQHP ELSNSQLLAD FLSPNGGETQ FLDKMLPDVN LGKIIKSVPG KLMKEKGQHL
     EPFIMNFFNS CESPKPKPSR PELTILSPTS ENNKKLFNDL FKNNANRSEN TERRQNQNYF
     MEMMTVEGVY DYLMYIGRVV FRIPDWLHHL LMGGRILFKN TLELYTDYYL HNKLEQLFEE
     HRLVSLITLL RDAVFCENTE PRSLQDKQKR AKQTFEEMMK YIPDLIGKCI GEEAKYEGIR
     LLFDGLQQPV LNKQLTYVLL DIGIQELFPE LSKGPKEASS MSSWM
//