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Database: UniProt
Entry: U3JQS0_FICAL
LinkDB: U3JQS0_FICAL
Original site: U3JQS0_FICAL 
ID   U3JQS0_FICAL            Unreviewed;       467 AA.
AC   U3JQS0;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   16-OCT-2019, entry version 40.
DE   SubName: Full=Potassium voltage-gated channel subfamily J member 5 {ECO:0000313|Ensembl:ENSFALP00000005124};
GN   Name=KCNJ5 {ECO:0000313|Ensembl:ENSFALP00000005124};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae;
OC   Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000005124, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000005124}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2013) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; AGTO01000852; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 59894.ENSFALP00000005124; -.
DR   Ensembl; ENSFALT00000005149; ENSFALP00000005124; ENSFALG00000004927.
DR   GeneTree; ENSGT00970000193368; -.
DR   OMA; DREWIPC; -.
DR   Proteomes; UP000016665; Unplaced.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0086089; F:voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization; IEA:Ensembl.
DR   GO; GO:0098914; P:membrane repolarization during atrial cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:1990573; P:potassium ion import across plasma membrane; IEA:Ensembl.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IEA:Ensembl.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003277; K_chnl_inward-rec_Kir3.4.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01330; KIR34CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000016665};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    121    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    196    219       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       85    224       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      231    401       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      408    467       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    426    446       Acidic. {ECO:0000256|SAM:MobiDB-lite}.
FT   SITE        210    210       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   467 AA;  53134 MW;  4D97451CC617E4FF CRC64;
     MRKWHIRPLE GTGNAVRGEL RGDCGSRSPA MAGDSRIFMS QDMDVGVTSR EPKKVPKQAR
     DDVPIATDRT RLISAEGKKP RQRYMEKSGK CNVHHGNVQE TYRYLSDLFT TLVDLKWRFN
     LLVFTMVYTI TWLFFGFIWW LIAYIRGDLD HLEDENWIPC VENLSGFVSA FLFSIETETT
     IGYGHRVITE KCPEGIVLLL VQAILGSIVN AFMVGCMFVK ISQPKKRAET LMFSNNAVIS
     MRDEKLCLMF RVGDLRNSHI VEASIRAKLI KSKQTKEGEF IPLNQTDINV GFDTGDDRLF
     LVSPLIISHE INEKSPFWEM SRTQLEKEEF EIVVILEGMV EATGMTCQAR SSYMDTEVLW
     GHRFTPVLTL EKDFYEVDYN SFHSTYETHT PACCAKELAQ SRREGQLLGH LPGLGQDTGT
     AREEQEQEQQ EEEQEEEEEE EEEEGRDPAG QSGANGTAGQ GKEEVPV
//
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