ID U3JTD4_FICAL Unreviewed; 685 AA.
AC U3JTD4;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=G2/M-phase specific E3 ubiquitin protein ligase {ECO:0000313|Ensembl:ENSFALP00000006038.2};
GN Name=G2E3 {ECO:0000313|Ensembl:ENSFALP00000006038.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000006038.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000006038.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000006038.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; U3JTD4; -.
DR Ensembl; ENSFALT00000006065.2; ENSFALP00000006038.2; ENSFALG00000005783.2.
DR GeneTree; ENSGT00950000182865; -.
DR OrthoDB; 2899995at2759; -.
DR Proteomes; UP000016665; Chromosome 5.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd15669; ePHD_PHF7_G2E3_like; 1.
DR CDD; cd15496; PHD_PHF7_G2E3_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR042013; PHF7/G2E3_ePHD.
DR InterPro; IPR042012; PHF7/G2E3_PHD.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12420:SF37; G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR12420; PHD FINGER PROTEIN; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 11..128
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 301..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78183 MW; 5EAE0B67E820EE08 CRC64;
MSTTSNFDVQ STFCVLCGRT DDCTEKYGEK RTYVEYNLTV HNYCLLMSSG IWQRGEEDEG
VDGFLITDIR KEVKRAAKLK CNICRKKGAS IGCVAPKCKR SYHFPCGLQR ECIFQFMEDF
RSYCWDHRPV QEFTDQEPRG ASQCTICLDL VEHLPVYTVL KSPCCKNAWF HRECLQYQAL
SAGIFFFRCT VCNNKEKFQK EMLRMGIHIP ERDASWELEE NAYQDLLHCY QHCDVKRCLC
KKGRDYNEPD SKWEIKRCQY CGSRGTHLAC SSMQSWEENW ECMECRSIFA TSGKYSKQKK
RSLATSEKSN GTTCLLEEPS PKSPRQSSGS PRNFLLQSQK IMCQNLSPCS HRELPASNRM
TMSLSPVMSN RHLKERRREV CNILKELKVQ VKTKPTRLNI NAENIWSSAL KGFRQRMFSP
TNTIELLMLH LQNSSLFEGS SGKTLSLDFQ ALEENLYFEA GKMIAVSLVH GGPPPGFFSK
TLYNCLVYGP ENVKPSLEDV ADDDVAQTIK KIKYANSLSS LQSTLQDCCE FLAAAGCLRP
VTALCDKNML VNDILIYHVI KRVTLPLESF RQGLKTLGVL EKMQMRPNVF SSIFCHKSER
LSAKTICDLF TIHSTSDVNK VEGADFWMGY LQEVESGESV VTLEDILLFV TGSCYIPSIG
FDPEPTIKFL HIRSSLNVSF CCRQV
//
