ID U3JVU6_FICAL Unreviewed; 1905 AA.
AC U3JVU6;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=WD repeat domain 81 {ECO:0000313|Ensembl:ENSFALP00000006900.2};
GN Name=WDR81 {ECO:0000313|Ensembl:ENSFALP00000006900.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000006900.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000006900.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000006900.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 59894.ENSFALP00000006900; -.
DR Ensembl; ENSFALT00000006929.2; ENSFALP00000006900.2; ENSFALG00000006614.2.
DR eggNOG; KOG1786; Eukaryota.
DR eggNOG; KOG4190; Eukaryota.
DR GeneTree; ENSGT00930000151039; -.
DR HOGENOM; CLU_001454_0_0_1; -.
DR Proteomes; UP000016665; Chromosome 19.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44662; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR PANTHER; PTHR44662:SF1; WD REPEAT-CONTAINING PROTEIN 81; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 312..588
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 1606..1637
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 637..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1069..1141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1495..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1069..1087
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1139
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1175
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1905 AA; 210903 MW; 459B4AE00D83425C CRC64;
PPPPPPGMEG FLQSVEKDLN IDRRQLAPER THVSALVPVK WLQSLKERRV LPAACPRPEG
LSEVELRTFL QHSVQKLPAG WTRVEIHGLR KARLGYPLRA QPPEQRCGGS GDTLHGFMRS
VATQNYHNLW GRAHRLYARP YRRPDAPPTV PALDALRAAL HRAYGCPVLQ VGRNVPGTSP
AKESVAKGVP LCPNVLQAEA LLESADMMYI VYPYVQYCLH DVVTFSPAKL TNSHAKILFL
LFHVLQAMKA CHQAGLACGD FSLRDVAVDE KLCSRLRVNF RGYEGPGQEE ENLEGGLERE
SKQSCVQRQE VTCSACQKDL RDLVLQWVHG QVSNFDYLMR LNSLAGRRMG DPNYHPVLPW
VVDFTTKNGK FRDLRKSKFR LNKGDKQLDF TYEMTKQAFV AGGSSGEQLH VPHHISDVLS
DITYYVYTAR RTPKAVLCCH VRSQWEPNEY PASMERMQSW TPDECIPEFY TDPSIFRSIH
PDMPDLDVPS WCSSYEEFIQ VHRMLLESRE VSQDLHHWID LTFGYKLLGK DAVKEKNVCL
HLVDNHTHLT TYGVVQLFDQ PHPRRMVGPA YTPAEAPAIA RPLLQNIRET VVLEDIQGQV
TDAVNGLVLE ATPSETTWSG EKPMAGEDDL EQGTEALDSI SAPGRPPDQP CATVPPAQPS
TLPAYATDSK SSGVRPLRRS KAGAVDQLDM KITLPEGFNP LQALEELEKL DNFLVKGLSS
EMQLMEQTWE EPPLGLSDLF QRDMQALGIL VAEIIFAPRL RPSKPDASLW ERFLMVRNLC
RYHPKEIPAP LQHVLHVLLQ LSVPAEKLLK SRPGKGAVQL FEYKPISQGL PPPCPTQLLS
PFSSIVPFPT YFPALHKFIF TYQAKKIEDE GQGRELVFQL WQQLEGILSE ITPEGLEILL
PFILSLMSEE NTAVYAAWYL FEPIAKSLGP KNANKYLLKP LIGAYETPCS RHGRFYLYTD
CFVAQLIVRL GLQPFLLNLL PHILQILVGI ESSREESKSF LGTAEDDESG GESPVSCVFG
EEIKMDVEHS SAALDLLDYT SGVSFHDQAY LPEGEDFQSG LYVGESLQPQ EQESLSLGRL
SDKSSASEVS LGEDRPADGD SQKDKSSLKS MDSSQDLKQS EESEEEEEEH EEEEHEDAAV
DAELTVVVDA AGASVDVTLA DDSSEPEDGE GEELPDHSDD KEQTILLDTA CKMVRWLSAK
LGPTVTSRFI ARNLLRLLTS CYIGPTRQQF VPSSDETSPL STGNIYQKRP VLGDQVSKPV
LACLVHVAYL YGEPVLTYQY LPYISYLVAP GGGSGGVRLN SRKEAGLLAA VTLTQKIVVC
LSDTTLMDIL PKISQEVLLP VLGFLTSPAV GFPSGAQARV VLCVKTVSLI ALICLRIGQE
MVQQHLSDTV RNFFGAFSLL QELQEQVKSL SSCEVPVIEV PLSDGKLLSV DPSVLVELQK
VFNPEMAYIT YIPFSCLLGD VIQTVVPNHS LVEKLASLHL ENVNPQNLQV VGLEQTPSSD
QDPRGAEPFS SPQEDTHSGT FGSVLVGNRI QVPVDTQREG LGVLRLSAGA DGFAASSCSE
DNALKQELPR STHMLCGNWL AYWQYEIGVS QHDPRFHFHQ IKLQSFSGHC GAIKCVAPLG
SEDFFLSGSK DKTVRLWPLY NYGDGTSEVP PRFTYAEHKK SVFYVSQLEA PQHVVSCDGT
VHIWDQFTGK LLRTFDELDS KVPITAVTTM PPPYHSISVA SADSVLRFID HRKPGLQHEF
RLASGVSAGL IRCLAVSPSG RSLMAGFSSG FIVLLDTRTG LIMRGWPAHE GDILQIKAAE
GNVLISSSSD HSLTVWKELE QKPLHHYKSA SEPIHAFDLY GNEVVTGTVA NKIGVYSMLE
SSALPTSTTK LSSENFRGTL TSLAVLPTKC HLLLGSDNGI IRLLA
//
