ID U3K1Z8_FICAL Unreviewed; 1065 AA.
AC U3K1Z8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=SLIT and NTRK like family member 3 {ECO:0000313|Ensembl:ENSFALP00000009052.2};
GN Name=SLITRK3 {ECO:0000313|Ensembl:ENSFALP00000009052.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000009052.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000009052.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000009052.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SLITRK family.
CC {ECO:0000256|ARBA:ARBA00010439}.
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DR AlphaFoldDB; U3K1Z8; -.
DR Ensembl; ENSFALT00000009091.2; ENSFALP00000009052.2; ENSFALG00000008679.2.
DR eggNOG; ENOG502QYY5; Eukaryota.
DR GeneTree; ENSGT00940000158681; -.
DR HOGENOM; CLU_012706_0_0_1; -.
DR Proteomes; UP000016665; Chromosome 9.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0098982; C:GABA-ergic synapse; IEA:Ensembl.
DR GO; GO:0099634; C:postsynaptic specialization membrane; IEA:Ensembl.
DR GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR GO; GO:0097116; P:gephyrin clustering involved in postsynaptic density assembly; IEA:Ensembl.
DR GO; GO:0072578; P:neurotransmitter-gated ion channel clustering; IEA:Ensembl.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR GO; GO:1905606; P:regulation of presynapse assembly; IEA:Ensembl.
DR GO; GO:0099560; P:synaptic membrane adhesion; IEA:Ensembl.
DR GO; GO:0051932; P:synaptic transmission, GABAergic; IEA:Ensembl.
DR GO; GO:0072553; P:terminal button organization; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR043326; Slitrk.
DR PANTHER; PTHR45773:SF6; SLIT AND NTRK-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR45773; SLIT AND NTRK-LIKE PROTEIN 4-RELATED; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1065
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032918283"
FT DOMAIN 233..283
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 327..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 961..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..359
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1065 AA; 99877 MW; 2A62E8F9E6378660 CRC64;
MMKPSTAETL HKGRMLWIIL LSTIALAWTT PIPLIEDSEE LDEPCFDPCY CEVKESLFHI
HCDNKGFINI SQITESWSRP FKLYLQRNSM RKLYTNSFLH LNNAVSINLG NNALQDIQTG
AFNGLRVLKR LYLHENKLDI FRNDTFLGLE SLEYLQADYN VIKRIESGAF RNLSKLRVLI
LNDNLIPMLP TNLFKSVSLT HLDLRGNRLK VLSYRGMLDH IGRSLMEIQL EENPWNCTCE
IVQLKSWLER IPYTALVGDI TCETPFHFHG KDLREIKRSK LCPMLSDSEV EASLGIPQLS
SSKENAWPTK PSSMLSSFHF TASSVEYKTS NKQPKPTKQP RAPRPPPTPR GLYPGPNQPP
VAAYQTRPPI PIICPTGCSC NLHINDLGLT VNCKERGFHN ISELLPRPLN AKKLYLSGNL
IQKIYRSDFW NFSSLDLLHL GNNRISYVQD GAFINLPNLK SLYLNGNDIE RLTPGMFRGL
QSLHYLYFEY NLIREIQPAA FSLMPNLKLL FLNDNLLRTL PTDAFAGTSL ARLNLRNNHF
LALPVAGVLE HLHAIVQIDL KLNPWDCTCE LVPLKQWLEA LSSVSVVGEV LCASPEGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG
GGGGGGGGGG GGVPRDRDRP PPCAVGFVDC LYGTVPKLKE LHVHPPGMQY PDLQQDARLK
ETLLFAAGKG FPDHQTPTSE YLELRAKLQT KPDYLEVLEK TTYRF
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