ID   U3K2Z7_FICAL            Unreviewed;       960 AA.
AC   U3K2Z7;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=Ataxin 2 {ECO:0000313|Ensembl:ENSFALP00000009401.2};
GN   Name=ATXN2 {ECO:0000313|Ensembl:ENSFALP00000009401.2};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000009401.2, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000009401.2, ECO:0000313|Proteomes:UP000016665}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23103876; DOI=10.1038/nature11584;
RA   Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA   Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA   Wolf J.B.;
RT   "The genomic landscape of species divergence in Ficedula flycatchers.";
RL   Nature 491:756-760(2012).
RN   [2] {ECO:0000313|Ensembl:ENSFALP00000009401.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ataxin-2 family.
CC       {ECO:0000256|ARBA:ARBA00007503}.
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DR   AlphaFoldDB; U3K2Z7; -.
DR   STRING; 59894.ENSFALP00000009401; -.
DR   Ensembl; ENSFALT00000009441.2; ENSFALP00000009401.2; ENSFALG00000009001.2.
DR   eggNOG; KOG2375; Eukaryota.
DR   GeneTree; ENSGT00940000156812; -.
DR   HOGENOM; CLU_003766_2_0_1; -.
DR   Proteomes; UP000016665; Chromosome 15.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   InterPro; IPR009818; Ataxin-2_C.
DR   InterPro; IPR045117; ATXN2-like.
DR   InterPro; IPR009604; LsmAD_domain.
DR   InterPro; IPR047575; Sm.
DR   InterPro; IPR025852; SM_dom_ATX.
DR   PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR   PANTHER; PTHR12854:SF11; ATAXIN-2; 1.
DR   Pfam; PF06741; LsmAD; 1.
DR   Pfam; PF07145; PAM2; 1.
DR   Pfam; PF14438; SM-ATX; 1.
DR   SMART; SM01272; LsmAD; 1.
DR   PROSITE; PS52002; SM; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665}.
FT   DOMAIN          2..79
FT                   /note="Sm"
FT                   /evidence="ECO:0000259|PROSITE:PS52002"
FT   REGION          194..617
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          783..826
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          844..865
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..223
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..278
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..443
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..465
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..480
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..503
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..554
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        555..572
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        573..595
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        799..826
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        850..865
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   960 AA;  103980 MW;  AA9860BA03D060F4 CRC64;
     MRMVHILTSV VGSKCEVQVK NGGIYEGVFK TYSPKCDLVV DAAHRKTAES SLGPKREDIL
     ESILFKSSDF VMVHFKDMDT NYARRDAFTD SAISAKVNGE HKEKDLEPWD GGENTASEEL
     EALETDVSNG WDPNDMFRYN EENYGVVSTY DSSLSSYTVP LERDNSEEFL KREARATQLA
     EEIESSAQYK ARVALENDER TEEEKYTAVQ RNANEREGHG VNTRENKYIP PGQRNRDVMS
     WGSGRQNSPR MGQSGSGPPI SRSGSHTSEF SPNSGADQRV VNGGPPRMSP KAQRHPRGHR
     VSTGRGTISS GLEFVSHNAP GEASTAAVAR GSPSGGTWSS VVSGVPRLSP KTHRPRSPRQ
     SSTPMGPALP SPQPGSIPTE SVAMPVPAAS PTPASPASNR AVTPSSEAKD TRLQDQRQNT
     AAGNKENIKP SETSPSFSKP ENKGVSPIVS EHRKQIDDLK KFKNDFRLQS SSSSDAVDQL
     LNKTREGEKS RDVVKEKTES TPKESIIEAG SNTNSNGGSS KPNSPSISPS MSNSSEQKRG
     PEVTSQGVQT SGPGSKQDKE DKEEKKDTSE QVRKSTLNPN AKEFNPRSFA QPKPSTTPTS
     PRPQAQPSPS MVGHQQPTPV YTQPVCFAPN MMYPVPVSPG VQPLYPIPMT PMPVNQAKTY
     RAGKVPNMPQ QRQDQHHQST MMHPASAAGP PIVATPPAYS TQYVAYSPQQ FPNQPLVQHV
     PHYQSQHPHV YSPVIQGNAR MMAPPAHAQP GLVSSSATQY GAHEQTHAMY VSTGSLAQQY
     AHPNATLHPH PPHPQPSATP TGQQQSQHAG SHPAPSPVQH HQHQAAQALH LANPQQQSAI
     YHAGLAPTPP SMTPGSNTQS PQNNFPTAQQ TVFTIHPSHV QPAYTNPPHM AHVPQAHVQS
     GMVPSHPTAH APMMLMTTQP PGGPQAALAQ SALQPIPVST TTHFPYMTHP SVQAHHQQQL
//