ID   U3K4J2_FICAL            Unreviewed;       594 AA.
AC   U3K4J2;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Intracisternal A particle-promoted polypeptide {ECO:0000313|Ensembl:ENSFALP00000009946.1};
GN   Name=IPP {ECO:0000313|Ensembl:ENSFALP00000009946.1};
OS   Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX   NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000009946.1, ECO:0000313|Proteomes:UP000016665};
RN   [1] {ECO:0000313|Ensembl:ENSFALP00000009946.1, ECO:0000313|Proteomes:UP000016665}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23103876; DOI=10.1038/nature11584;
RA   Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA   Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA   Wolf J.B.;
RT   "The genomic landscape of species divergence in Ficedula flycatchers.";
RL   Nature 491:756-760(2012).
RN   [2] {ECO:0000313|Ensembl:ENSFALP00000009946.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   RefSeq; XP_005050159.1; XM_005050102.1.
DR   AlphaFoldDB; U3K4J2; -.
DR   STRING; 59894.ENSFALP00000009946; -.
DR   Ensembl; ENSFALT00000009986.2; ENSFALP00000009946.1; ENSFALG00000009544.2.
DR   GeneID; 101813831; -.
DR   KEGG; fab:101813831; -.
DR   CTD; 3652; -.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000158629; -.
DR   HOGENOM; CLU_004253_14_1_1; -.
DR   OMA; CYDPRDN; -.
DR   OrthoDB; 5472491at2759; -.
DR   Proteomes; UP000016665; Chromosome 8.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   CDD; cd18466; BACK_KLHL27_IPP; 1.
DR   CDD; cd18256; BTB_POZ_KLHL27_IPP; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR030104; BTB_POZ_IPP.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR047067; IPP_BACK.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          47..114
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   594 AA;  65213 MW;  2E589AD1E417D534 CRC64;
     MAASAGTGKG GSGSSSSSSS SSSSSSERHA RLLLAQINRL RAGHSFCDVR LEVGPEAFSV
     HRLVLAASSP YFAALFAGGM KESGRDVVRI AGVEADTFHT LLDFIYTGVV SIAEHNVQEL
     IVAADMLQLT EVVELCCEFL KGQIDPLNCI GLFQFSEQIA CHDLMEFTES YIHAHFLEVQ
     SGEEFLALTK EQLVKILRSE DLSIEDEYQV FTAAMQWILK DVGKRKKYVV EVLEPVRFPL
     LPAQRLLKYI ESIPDFSLRV ALQTLLKEYC EVSKSPKENK VSSFLQASKG RPRRKARKYL
     YAVGGYTRLQ GGRWSDSRAL SCVERFDTFS HYWTTVSSLH QARSGLGVAV VGGMVYAIGG
     EDNSMIFDCT ECYDPVTKQW STVASMNHPR CALGVCTCYG AIYALGGWIG AEIGNTIERF
     DPEENSWDVV GSMAKPRYCF GCCEMQGLIY VIGGISSEGV ELRSVEVYNP ISKRWSELAP
     MGTRRAYLGV AALNDCIYAV GGWNESQDAL ASVERYSFEE EKWVEVASMK IPRAGVCVVA
     VNGLLYASGG RAPSPDFAAP VTSDSVEVYN PHMDCWTEIA NMITSRCEGG VAVL
//