ID U3KAE5_FICAL Unreviewed; 1928 AA.
AC U3KAE5;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Anaphase promoting complex subunit 1 {ECO:0000313|Ensembl:ENSFALP00000011999.2};
GN Name=ANAPC1 {ECO:0000313|Ensembl:ENSFALP00000011999.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000011999.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000011999.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000011999.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC1 family.
CC {ECO:0000256|ARBA:ARBA00010547}.
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DR STRING; 59894.ENSFALP00000011999; -.
DR Ensembl; ENSFALT00000012048.2; ENSFALP00000011999.2; ENSFALG00000011500.2.
DR eggNOG; KOG1858; Eukaryota.
DR GeneTree; ENSGT00390000016757; -.
DR HOGENOM; CLU_001202_1_0_1; -.
DR Proteomes; UP000016665; Chromosome 3.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR024990; Apc1.
DR InterPro; IPR048971; Apc1_3rd.
DR InterPro; IPR041221; APC1_C.
DR InterPro; IPR046794; Apc1_MidN.
DR InterPro; IPR049255; Apc1_N.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR002015; Proteasome/cyclosome_rpt.
DR PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR Pfam; PF12859; ANAPC1; 2.
DR Pfam; PF21282; APC1_3rd; 1.
DR Pfam; PF18122; APC1_C; 1.
DR Pfam; PF20518; Apc1_MidN; 1.
DR Pfam; PF01851; PC_rep; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 62..160
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 559..638
FT /note="Anaphase-promoting complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12859"
FT DOMAIN 640..965
FT /note="Anaphase-promoting complex subunit 1 middle"
FT /evidence="ECO:0000259|Pfam:PF20518"
FT DOMAIN 1601..1686
FT /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21282"
FT DOMAIN 1720..1879
FT /note="Anaphase-promoting complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18122"
FT REGION 256..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1928 AA; 214045 MW; 1EDE773AD980C915 CRC64;
DWIRPHPTSA LSLGSKGLRR LQPAPELCSS DGAAGLVGSL REVTIHDRHR ESWQLRKGIS
DVGEEVDYDE ELYVASNVVI WSKGSRSQAS AVYKAFTVDS PVLQALWCDF TIPQEKLDKA
DGSEEIVEKC ICILQNSCIN VHSMEGKDYI AALPFQVTSA LLFVHNFYLH LHSPALEPLP
TMFSMLHPLD EITPLVWKSG GVFGSSRVQY VADHTLRIVF LSPEPSIVMT YDTVQSLHTV
WALRRVKPEE QSLVLKFPEQ GGTPQHMATS SSLTAHLRSL SKGDSPGGSP FQNYSSIHSQ
SRSSSSPNLQ SRSPTISNMA ALSRSHSPAL GVHSFSGVQR FNFSSSAQSP RRPSVTHSPN
SICNDSFLVP ETEPIVPELC IDHLWTETLP SMRSEKNSQA SKVFISTDLC GQKFLCFLVE
SQLQLRCVKF QESNDKSQLI FGSVTNIPAK DAAPVEGIDT LLVLEGSGNL VLYSGVVRVG
KVFIPGLPAP SLTMSNPMPR PSTPLDSVST PSKPLNKHLG PLEESVLLSP VPELRDSSKL
HDSPYVEDCT FQQLGTFIQA LRDPVHNRVT LELSNNTMVR ISIPEIATSE LVKRCLQGLK
AILPKETAVQ MLVKWYNAYN APGGPSYHSE WNLFVTCLMN MMGYNTERLC WTRNLDFEGS
LSPVIAPKKA RPSETGSDED WEYLLSSDYH RNFESHPIAK ALCLDPLEVS ASKDDFSQSL
SLDSSTLLFS HIPAIFFVLH LIYEELKLNS LMGEGLRSLV VLLVQLARDL KLEAYMDYYY
RDYPALVKTS RQTCIIDQVQ TGFMLHPSFF SAEPPSIFQW LSSCLKGEGV QPYPYLPGIC
ERSKLVVLSV ALYILGDESA VLNEASHYLY KITSGQRKQQ MEQDDKRYGS FWCCSILLAS
PSFSSLAEKL VLWMTSVGFT LRDLESLPFG VALPIRDAIY QCREQPASDW PEAVCLLIGR
QDLSKQAWEG SLQKGKSSVG TVLSSDIPSA AESEEDEDGM NDMNEEVMSL IWSEDLRVQE
VRRLLQSARP VRVNVVQMPE ASDHEYIEEK ENRLLQLCQR TMALPVGRGM FTLFSYHPVP
TEQLPIPKLN LTGRAPPRNT TVDLNSGNID VPPNMACWAS FHNGVAAGLK IAPASQIDSA
WIVYNKPKMA ELANEYAGFL MALGLNGHLT KLATLNIHDY LTKGHEMTSI GLLLGVSAAK
LGTMDMAITR LLSIHIPALL PPTSTELDVP HNVQVAAVVG IGLVYQGTAH RHTAEVLLAE
IGRPPGPEME YCTDRESYSL ASGLALGMVC LGHGSNLIGM SDLNVPEQLY QYMVGGHRRF
QAGMHREKHK SPSYQIKEGD TINVDVTCPG ATLALAMIYL KTNNRSIADW LKAPDTMYLL
DFVKPEFLLL RTLARCLILW DDILPNSKWV NSNVPQIIRE NIISLHATEL PSSEDLSLET
LAQAHVYIIA GACLSLGFRF AGSENLAAFQ CLYKYATDFL KCLSAPTASI TGHYNLETCL
SVLLLALAMV MAGSGNLKVL QLCRFMHKKT GGEMNYGFHL AHHMALGLLF LGGGRYSLST
SNSSIAALLC ALYPHFPVHS TDNRYHLQAL RHLYVLAAEP RLLTPVDVDS NTPCYALIEV
TYKGTQWYGE ATEELMAPTL LPELHLLKQI RVKGPRYWEL LIDLSKGTTH LQSILSKGGI
LYVKLRAGQL SYKEDPMGWR SLLAQTVAHR SCEARAFKPE AISAFTSDPA LFSFADYFCK
PTVNMGQKQE ILDLFSSILY ECVTQENPEM LPTYIAIDQA VRRLERREMS ETFELWQMKL
VLEFFSSRSH QERMSRNPTR GLFMNSEFLP VMKCTIDNTL DQWLQAGGDV SLHSYLSGQA
PEESQLSMLA CFLIYHSVPT PGQLAAGGLQ GSRNFSELLL KLRRLHVPVR ALLRLAPLLL
GNPQAMVL
//
