ID U3KDW0_FICAL Unreviewed; 223 AA.
AC U3KDW0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=GTP-binding protein SAR1a {ECO:0000256|ARBA:ARBA00040180};
GN Name=SAR1A {ECO:0000313|Ensembl:ENSFALP00000013214.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000013214.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000013214.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000013214.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with B3GAT1. {ECO:0000256|ARBA:ARBA00038792}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. SAR1 family.
CC {ECO:0000256|ARBA:ARBA00007507, ECO:0000256|RuleBase:RU003926}.
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DR AlphaFoldDB; U3KDW0; -.
DR STRING; 59894.ENSFALP00000013214; -.
DR Ensembl; ENSFALT00000013270.2; ENSFALP00000013214.2; ENSFALG00000012661.2.
DR eggNOG; KOG0077; Eukaryota.
DR GeneTree; ENSGT00940000155276; -.
DR HOGENOM; CLU_040729_6_0_1; -.
DR OrthoDB; 5349301at2759; -.
DR Proteomes; UP000016665; Chromosome 6.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:Ensembl.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0090110; P:COPII-coated vesicle cargo loading; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd00879; Sar1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR006687; Small_GTPase_SAR1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45684:SF6; GTP-BINDING PROTEIN SAR1A; 1.
DR PANTHER; PTHR45684; RE74312P; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51422; SAR1; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU003926};
KW ER-Golgi transport {ECO:0000256|RuleBase:RU003926};
KW Golgi apparatus {ECO:0000256|RuleBase:RU003926};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|RuleBase:RU003926};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Transport {ECO:0000256|RuleBase:RU003926}.
FT REGION 204..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 223 AA; 24690 MW; C9441AB6E9D98B01 CRC64;
MSFIFEWLYN GFSSVLQFLG LYKKSGKLVF LGLDNAGKTT LLHMLKDDRL GQHVPTLHPT
SEELTIAGMT FTTFDLGGHE QARRVWKNYL PAINGIVFLV DCADHSRLME SKVELNALMT
DETISNVPIL ILGNKIDRPE AISEEKLREI FGLYGQTTGK GNVPLKDLNA RPMEVFMCSV
LKRQGYVGEE HLLQVLGVVS SEKGLPGSPS GQILEDPLAT PSQ
//
