ID U3KGY8_FICAL Unreviewed; 779 AA.
AC U3KGY8;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Dipeptidyl peptidase like 10 {ECO:0000313|Ensembl:ENSFALP00000014292.2};
GN Name=DPP10 {ECO:0000313|Ensembl:ENSFALP00000014292.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000014292.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000014292.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000014292.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; U3KGY8; -.
DR STRING; 59894.ENSFALP00000014292; -.
DR Ensembl; ENSFALT00000014351.2; ENSFALP00000014292.2; ENSFALG00000013689.2.
DR eggNOG; KOG2100; Eukaryota.
DR GeneTree; ENSGT00940000154657; -.
DR HOGENOM; CLU_006105_4_1_1; -.
DR Proteomes; UP000016665; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF21; INACTIVE DIPEPTIDYL PEPTIDASE 10; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..481
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 563..766
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 779 AA; 88512 MW; 64AA00A42454BDD8 CRC64;
VYLNLYGPYH ELGSNSPPQR NWKGIAIALL VILVVCSLIT MSVILLTPGN LLLYFILLKV
CIKFSVCLLT AYFFVVADTA VVYKTRNGHV VELNVETNTT TLLLENTTFV TFKASRYSVS
PDLRFVLMAY DVKQVFHYSY TASYVIYNIH TREVWELNPP EVEDSVLQYA AWGVHGQQLI
YIFENNIYYQ PDVKSSSLRL TSSGKEGIIF NGIADWLYEE ELLRSHIAHW WSPDGERLAF
LTINDSLVPN MVIPRFTGGL YPKGKQYPYP KAGQTNPTVK LFVVNLYGPA HTLELMPPDS
FKSREYYITM VKWISNTKAV VRWLNRAQNI SILTVCETTT GACTRVKVCQ AKTMLHLQNE
EPVFSKDGSK FFMTVPVKQG GRGEFHHIAM FIVQLNPFGE QISVRHLTSG NWEVIKILAY
DENTQNIQVY FIVFFSTVKL GSLNRQCLSC NFMKDQCTYF SAKFSPMNRH FLLHCKGPGV
PVVSVHRTNN TENFYILENN PVLKEVVFKK KNYKTEIKML HIEDYEFPLQ LSLPKDFTDR
NQYALLLIID EAPGSQLVTD KFHIDWDSVL VNSDNVIVAR FDGRGSGFQG LKILQEVHRC
LGSVEVKDQI AAVESLLKQP FIDPKRLGIF GKGYGGYITS MILKSSERLF KCGAVVAPIT
DMKLYASAFS ERYLGIPSKD EITYQASSVL HNLHGLKEVD LLIVHGTADA KVHFQHSAEL
IKHLIKAGAN YTMQIYPDEG HNIASEKSKY HLYSTILGFF SACLKEETPI LPQEPEEDE
//
