ID U3KKJ0_FICAL Unreviewed; 533 AA.
AC U3KKJ0;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Potassium voltage-gated channel modifier subfamily S member 3 {ECO:0000313|Ensembl:ENSFALP00000015544.2};
GN Name=KCNS3 {ECO:0000313|Ensembl:ENSFALP00000015544.2};
OS Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Muscicapidae; Ficedula.
OX NCBI_TaxID=59894 {ECO:0000313|Ensembl:ENSFALP00000015544.2, ECO:0000313|Proteomes:UP000016665};
RN [1] {ECO:0000313|Ensembl:ENSFALP00000015544.2, ECO:0000313|Proteomes:UP000016665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23103876; DOI=10.1038/nature11584;
RA Ellegren H., Smeds L., Burri R., Olason P.I., Backstrom N., Kawakami T.,
RA Kunstner A., Makinen H., Nadachowska-Brzyska K., Qvarnstrom A., Uebbing S.,
RA Wolf J.B.;
RT "The genomic landscape of species divergence in Ficedula flycatchers.";
RL Nature 491:756-760(2012).
RN [2] {ECO:0000313|Ensembl:ENSFALP00000015544.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; U3KKJ0; -.
DR STRING; 59894.ENSFALP00000015544; -.
DR Ensembl; ENSFALT00000015609.2; ENSFALP00000015544.2; ENSFALG00000014929.2.
DR eggNOG; KOG3713; Eukaryota.
DR GeneTree; ENSGT00940000155979; -.
DR HOGENOM; CLU_011722_4_1_1; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000016665; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18428; BTB_POZ_KCNS3; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003971; K_chnl_volt-dep_Kv9.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF39; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 3; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01494; KV9CHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000016665};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 218..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 55..164
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 166..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 61018 MW; D999082889F3C4A5 CRC64;
MEKRMCHKSK SELNALTVSY VLFRFYVTSL GNSSGTRLSK MVYGEFFRRP GKDAELINLN
VGGFKQSVDQ STLLRFPHTR LGKLLKCHSE EAILELCDDY SVADKEYYFD RNPSLFRYVL
NFYYTGKLHV MEELCVFSFC QEIEYWGINE LFIDSCCSNR YQERKEEGPD KDWDQKSNDS
MDSSNEESSI FDKELEKFDN LCFGEIRKKI WVRMENPAYC LSAKLIAVSS LSVVLASIVA
MCIHSMPEFQ RLDANDREIG DPVLEAVEIT CIIWFTAELV IRLFTAPSQK KFWKKPLNII
DFVSIIPFYA TLAVDTKEEE SEDIENMGKV VQILRLMRIF RILKLARHSV GLRSLGATLR
HSYQEVGLLL LFLSVGISIF SVLVYSVEKD DDSSELQSIP ICWWWATISM TTVGYGDTYP
VTLAGKLLGT LCIICGILVV ALPITIIFNK FSKYYQKQKA IDRDQCNNDR KEKSNDLPYF
NIRDIYAKKM HSFISSLSSV GIVVSDQDST DASSIQDMED VYNTVSLEDG TGK
//
