ID U3KMN3_RABIT Unreviewed; 353 AA.
AC U3KMN3;
DT 13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=L1 transposable element RRM domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000026492.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000026492.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000026492.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000026492.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000026492.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02043239; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; U3KMN3; -.
DR SMR; U3KMN3; -.
DR Ensembl; ENSOCUT00000033445.2; ENSOCUP00000026492.2; ENSOCUG00000029665.2.
DR eggNOG; ENOG502S81Y; Eukaryota.
DR GeneTree; ENSGT01050000244818; -.
DR HOGENOM; CLU_062834_3_0_1; -.
DR InParanoid; U3KMN3; -.
DR Proteomes; UP000001811; Chromosome 11.
DR Gene3D; 3.30.250.20; L1 transposable element, C-terminal domain; 1.
DR Gene3D; 3.30.70.1820; L1 transposable element, RRM domain; 1.
DR Gene3D; 1.20.5.390; L1 transposable element, trimerization domain; 1.
DR InterPro; IPR042566; L1_C.
DR InterPro; IPR035300; L1_dsRBD.
DR InterPro; IPR043636; L1_RRM_dom.
DR InterPro; IPR004244; Transposase_22.
DR PANTHER; PTHR11505; L1 TRANSPOSABLE ELEMENT-RELATED; 1.
DR PANTHER; PTHR11505:SF216; LINE-1 RETROTRANSPOSABLE ELEMENT ORF1 PROTEIN; 1.
DR Pfam; PF17490; Tnp_22_dsRBD; 1.
DR Pfam; PF02994; Transposase_22; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
FT DOMAIN 168..263
FT /note="L1 transposable element RRM"
FT /evidence="ECO:0000259|Pfam:PF02994"
FT DOMAIN 267..330
FT /note="L1 transposable element dsRBD-like"
FT /evidence="ECO:0000259|Pfam:PF17490"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..171
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 353 AA; 41677 MW; 924A866963B75577 CRC64;
MPSNKHRNRG NKINDDTMMP PNKQNTPSRD YEDDEIEEMQ DTDFKKFMIR TFRSFQKQIL
ELQKSLLDKI ENLSCENQIL RKNQNETQKL VEQESVIVKR NQNEMKSSID QMTNTLESLK
NRMGEAEERI SDLEDREQER IQSNQRKEEE IRNLKNIVGN LQDTIKKTNI RVLGVPEGME
REKGLEGLFS EILAENFPGL EKDRDILVQE AHRTPSKHDQ KRSSPRHVVI KLSTVKQKEK
ILKCARVKRQ ITLRGSPIRL TADFSSETLQ ARREWRDIAQ VLREKNCQPR ILYPAKLSFV
NEGEIKTFHS KQKLKDFVAT HPALQKILKD VLHSETQKHG YQYERRERKN TYQ
//
