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Database: UniProt
Entry: U3UBI1_9POXV
LinkDB: U3UBI1_9POXV
Original site: U3UBI1_9POXV 
ID   U3UBI1_9POXV            Unreviewed;        75 AA.
AC   U3UBI1;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   12-AUG-2020, entry version 19.
DE   SubName: Full=Virion membrane component, involved in entry {ECO:0000313|EMBL:CCD83220.1};
GN   Name=I2L {ECO:0000313|EMBL:CCD83220.1};
GN   ORFNames=SQPV_0370 {ECO:0000313|EMBL:CCD83220.1};
OS   Squirrelpox virus.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae.
OX   NCBI_TaxID=240426 {ECO:0000313|EMBL:CCD83220.1, ECO:0000313|Proteomes:UP000144311};
RN   [1] {ECO:0000313|EMBL:CCD83220.1, ECO:0000313|Proteomes:UP000144311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red squirrel UK {ECO:0000313|EMBL:CCD83220.1};
RA   Darby A.;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCD83220.1, ECO:0000313|Proteomes:UP000144311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Red squirrel UK {ECO:0000313|EMBL:CCD83220.1};
RA   Darby A.C., McInnes C.J., Kjaer K.H., Wood A.R., Hughes M., Martensen P.M.,
RA   Radford A.D., Hall N., Chantrey J.;
RT   "The genome of epidemic Squirrel Poxvirus reveals novel virulence genes.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Late protein which probably plays a role in virus entry into
CC       the host cell. {ECO:0000256|ARBA:ARBA00004101}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Virion membrane
CC       {ECO:0000256|ARBA:ARBA00004381}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004381}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I2 family.
CC       {ECO:0000256|ARBA:ARBA00007048}.
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DR   EMBL; HE601899; CCD83220.1; -; Genomic_DNA.
DR   RefSeq; YP_008658462.1; NC_022563.1.
DR   GeneID; 18158397; -.
DR   KEGG; vg:18158397; -.
DR   Proteomes; UP000144311; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009175; Poxvirus_I2.
DR   Pfam; PF12575; Pox_EPC_I2-L1; 1.
DR   PIRSF; PIRSF003766; VAC_I2L; 1.
PE   3: Inferred from homology;
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000144311};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW   Virion {ECO:0000256|ARBA:ARBA00022844};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00022595}.
FT   TRANSMEM        48..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   75 AA;  8036 MW;  E9681BA2E9743585 CRC64;
     MDKLCAAVFG VFISSSEEDL DGFVDVVTAV LADKPVRKGP AGDSWLPYLL IGLAVLIGVI
     AVMVYAVPWK SRIQN
//
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