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Database: UniProt
Entry: U4K3A9_9VIBR
LinkDB: U4K3A9_9VIBR
Original site: U4K3A9_9VIBR 
ID   U4K3A9_9VIBR            Unreviewed;       905 AA.
AC   U4K3A9;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   20-JUN-2018, entry version 31.
DE   RecName: Full=Aldehyde-alcohol dehydrogenase {ECO:0000256|PIRNR:PIRNR000111};
GN   Name=adhE {ECO:0000313|EMBL:CCO57051.1};
GN   ORFNames=VIBNI_A0888 {ECO:0000313|EMBL:CCO57051.1};
OS   Vibrio nigripulchritudo.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=28173 {ECO:0000313|EMBL:CCO57051.1, ECO:0000313|Proteomes:UP000016895};
RN   [1] {ECO:0000313|EMBL:CCO57051.1, ECO:0000313|Proteomes:UP000016895}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SnF1 {ECO:0000313|Proteomes:UP000016895};
RX   PubMed=23739050; DOI=10.1038/ismej.2013.90;
RA   Goudenege D., Labreuche Y., Krin E., Ansquer D., Mangenot S.,
RA   Calteau A., Medigue C., Mazel D., Polz M.F., Le Roux F.;
RT   "Comparative genomics of pathogenic lineages of Vibrio
RT   nigripulchritudo identifies virulence-associated traits.";
RL   ISME J. 7:1985-1996(2013).
CC   -!- SIMILARITY: In the C-terminal section; belongs to the iron-
CC       containing alcohol dehydrogenase family.
CC       {ECO:0000256|PIRNR:PIRNR000111}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the aldehyde
CC       dehydrogenase family. {ECO:0000256|PIRNR:PIRNR000111}.
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DR   EMBL; FO203526; CCO57051.1; -; Genomic_DNA.
DR   RefSeq; WP_004402150.1; NZ_JXXT01000026.1.
DR   EnsemblBacteria; CCO57051; CCO57051; VIBNI_A0888.
DR   GeneID; 29461166; -.
DR   KEGG; vni:VIBNI_A0888; -.
DR   PATRIC; fig|1260221.3.peg.853; -.
DR   KO; K04072; -.
DR   Proteomes; UP000016895; Chromosome.
DR   GO; GO:0008774; F:acetaldehyde dehydrogenase (acetylating) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006066; P:alcohol metabolic process; IEA:InterPro.
DR   GO; GO:0015976; P:carbon utilization; IEA:InterPro.
DR   CDD; cd08178; AAD_C; 1.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 2.
DR   InterPro; IPR034789; AAD_C.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012079; Bifunc_Ald-ADH.
DR   Pfam; PF00171; Aldedh; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   PIRSF; PIRSF000111; ALDH_ADH; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
DR   PROSITE; PS00060; ADH_IRON_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000016895};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000111,
KW   ECO:0000313|EMBL:CCO57051.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016895}.
FT   DOMAIN        5    402       Aldedh. {ECO:0000259|Pfam:PF00171}.
FT   DOMAIN      458    849       Fe-ADH. {ECO:0000259|Pfam:PF00465}.
FT   COILED        9     29       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   905 AA;  97575 MW;  695B627075151EF2 CRC64;
     MPVTNLAELD AMIARVKAAQ AEFATYSQEQ VDKIFRAASL AANQARIPLA QQAVEESGMG
     IVEDKVIKNH FASEYIYNKY KDEKTCGILD EDESLGTMTI AEPAGIICGI VPTTNPTSTA
     IFKSLISLKT RNAIIFSPHP RAKNSTNDAA KLVLEAAVAA GAPKDIIGWI DQPSVELSNA
     LMKHDDIALI LATGGPGMVK AAYSSGKPAI GVGAGNVPVV IDESADIKRA VASILMSKTF
     DNGVVCASEQ AAIVVDEVYD EVKERFASHK AYVLSKDEAA KVRKVLLIDG NLNAKIVGQP
     APAIAEMAGV TVPADTKVLV GEGLGKVSYD DEFAHEKLSP TLGLFRADDF EDAVAQAVTM
     VEIGGIGHTS GLYTDQDKNA DRVRYFGDKL KTARILINIP TTHGGIGDLY NFNVAPSLTL
     GCGSWGGNSI SENVGPKHLI NKKTVAKRAE NMLWHKLPKS VYFRRGSLPV ALGDLEGKKR
     AFLVTDRFLF NNGYADETIN ILKANGMEVQ TFFDVEADPV LSAVQKGADA MNSFQPDVII
     ALGGGSPMDA AKIMWVMYEH PETAFEDLAM RFMDIRKRIY KFPKMGQKAE MVCIPTTSGT
     GSEVTPFAVV TDDKTGAKYP LADYELTPQM AIVDANLVMN MPKSLCAFGG YDAVTHALEA
     YVSVLANEYS DGQALQALKM LKEYLPSSYA NGANDPIARE KVHNAATIAG IAFANAFLGV
     CHSMAHKIGA EFHLAHGMTN AMLIDNVVRY NANDNPTKQT AFSQYDRPQA RRRYAEVADH
     LELSQPGDRT AQKIERLVSW LDELKTNLDI PKSIQAAGVN EADFLAVVDR LAVDAFDDQC
     TGANPRYPLI SELKEVMLAA YYGKPYIEGE TFEGTTVIKK KADQVAAKAA PKAAAKAPKK
     AKAEA
//
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