ID U4K751_9VIBR Unreviewed; 472 AA.
AC U4K751;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative Tyrosinase (Melanin production) {ECO:0000313|EMBL:CCO61157.1};
DE EC=1.14.18.1 {ECO:0000313|EMBL:CCO61157.1};
GN ORFNames=VIBNI_B1404 {ECO:0000313|EMBL:CCO61157.1};
OS Vibrio nigripulchritudo.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=28173 {ECO:0000313|EMBL:CCO61157.1, ECO:0000313|Proteomes:UP000016895};
RN [1] {ECO:0000313|EMBL:CCO61157.1, ECO:0000313|Proteomes:UP000016895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SnF1 {ECO:0000313|Proteomes:UP000016895};
RX PubMed=23739050; DOI=10.1038/ismej.2013.90;
RA Goudenege D., Labreuche Y., Krin E., Ansquer D., Mangenot S., Calteau A.,
RA Medigue C., Mazel D., Polz M.F., Le Roux F.;
RT "Comparative genomics of pathogenic lineages of Vibrio nigripulchritudo
RT identifies virulence-associated traits.";
RL ISME J. 7:1985-1996(2013).
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DR EMBL; FO203527; CCO61157.1; -; Genomic_DNA.
DR RefSeq; WP_022561632.1; NC_022543.1.
DR AlphaFoldDB; U4K751; -.
DR STRING; 28173.VIBNI_B1404; -.
DR KEGG; vni:VIBNI_B1404; -.
DR PATRIC; fig|1260221.3.peg.5007; -.
DR eggNOG; ENOG5030I5T; Bacteria.
DR OrthoDB; 2874181at2; -.
DR Proteomes; UP000016895; Chromosome 2.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004503; F:tyrosinase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF76; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:CCO61157.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016895}.
FT DOMAIN 70..88
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 239..250
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 472 AA; 53543 MW; 4B16FDDF1F9C02DB CRC64;
MTTVAKLNYR RKQAGLPLIR FNLLKLNPED VQDLRDAYAA MYEISELAVG DKRGYSALAR
AHGYDQDLCH DLDWAFLTWH RSYVYSFEKA LNTALKWKRE DPDLELTLPY WDWTQFKTST
HASNGLPKLL NELTYTNADG DETDNPLARA KSLYRVISQG LSGDEEFTHR YPDQFRQNIP
VLKNEVDRYL TNPSFVRFQA DLDRGAHGAI HVFVGGQNSN SPLPANSGDM SRVISASYDP
IFWLHHCMVD KIWADWQTLH PHTNIPQIIL DHVVYDSRIG SDLIDHEETL RYIYSEDSVE
TAVADTGTVD TITPKPLSAG VHHVKELSLG SVEAGFVRAQ LDFLRLRPPK NSFEIRAYID
NPGCNESTGY DDPSFAGRLM LFGHGQCHGA PGHCNPSLAT RDKYDLRSKH ALRYVHTRYS
MDVTSGLRRY IGRKKSIAHL KIHLLILDCE NQVVASDSIQ YDGCALRTFA KG
//
