ID U4L0J7_PYROM Unreviewed; 293 AA.
AC U4L0J7;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Similar to Spermidine synthase acc. no. Q9Y8H7 {ECO:0000313|EMBL:CCX07718.1};
GN ORFNames=PCON_07307 {ECO:0000313|EMBL:CCX07718.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX07718.1};
RN [1] {ECO:0000313|EMBL:CCX07718.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX07718.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX07718.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867, ECO:0000256|RuleBase:RU003836}.
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DR EMBL; HF935364; CCX07718.1; -; Genomic_DNA.
DR AlphaFoldDB; U4L0J7; -.
DR STRING; 1076935.U4L0J7; -.
DR eggNOG; KOG1562; Eukaryota.
DR OMA; FLYHEMM; -.
DR OrthoDB; 1126121at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00198; Spermidine_synth; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001045; Spermi_synthase.
DR InterPro; IPR030668; Spermi_synthase_euk.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR NCBIfam; NF037959; MFS_SpdSyn; 1.
DR NCBIfam; TIGR00417; speE; 1.
DR PANTHER; PTHR11558:SF11; SPERMIDINE SYNTHASE; 1.
DR PANTHER; PTHR11558; SPERMIDINE/SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR PIRSF; PIRSF000502; Spermidine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 12..248
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 167
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 293 AA; 33256 MW; 14B8E9AE711483A2 CRC64;
MSTEIVHPTI QDGWFREINH MWPGQAMTLK VEKVLHHEKS LYQDVLIFKS TDYGNVLVLD
NVIQCTERDE FSYQEMITHL AMNSHPNPKK VLVIGGGDGG VLREVVKHEC VEEAILCDID
EAVIRLSKQF LPHMAAGFEH PKTTVHVGDG FKFLEDYKNT FDVIITDSSD PDGPAEALFQ
KSYFELLNAA LKEGGVITTQ GSENQWLHLK LITELKKSCR EVFPTVEYAY TTIPTYPSGQ
IGFMVCSKDA NRDVSKPLRS LPEDEENKRY RYYNSKIHEA SFVLPNFAKL ALA
//
