ID U4L0M3_PYROM Unreviewed; 689 AA.
AC U4L0M3;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN ORFNames=PCON_07337 {ECO:0000313|EMBL:CCX07748.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX07748.1};
RN [1] {ECO:0000313|EMBL:CCX07748.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX07748.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX07748.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560}.
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DR EMBL; HF935371; CCX07748.1; -; Genomic_DNA.
DR AlphaFoldDB; U4L0M3; -.
DR STRING; 1076935.U4L0M3; -.
DR eggNOG; KOG3818; Eukaryota.
DR OMA; PEDGAWF; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 417..643
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 75892 MW; 51DDB4F53F58F9F2 CRC64;
MPPVQPNPKN KTSLTTFLRR APSAPAAAAS SQISSDPFEP LARSTPVRSS PAPVERPAPR
SLAVDIPPSV LRPIAFRVFT KKHNLTLKSD ALTLLCQFIG RRCGAEWRDS GSGEKLLDEV
ARRWKRAETA GKILVDGGDA LKAVLKGMDV PGGDATGRSP LSRTSSTLSI DGGDIPSSML
LGGVQDTEMP EAEREEIEDA VDPAEYFKIV DAFEQPKMVY NMNKKLFERG PKPSLFPPPT
AKTTLFRTRY NVIHSRILRN DSFLAPTYSK SSNANPKSFY KLTSISALLG RSGQNFLLFG
MLQYSPSGIL SLYDPTGEIE LDTKLTQPLP DENANWFVPG MFVILDGMYE EDGRFTVYTA
LSPPPERREA SAEIFGHVDF LGNGVSLDMS SPSGGGQQGS MMRKVELALT HIRWVAIGEV
TLDQPKTLEA LRKLFEKYSK EPPMLFILSG NFSSVPVAPG DNNAIRGYKE NFDALASLLV
EFPMICMNST LLFIPGDHDP WASAFSGGST AAWPRKAVPE VFLNRVKRVA KHVKCASSPC
RLGYFTSEVV VCRDDIVGRL QRTQIRFAKP AQDDEMEVDG AGVEPTQSAT QVDDDTKLAR
KLVKTVLDQG YLSPFLGNKR PVLWDFAHTL GLYPLPSALL LIEPFAAPFA VTYEGCHVIN
PGKFTHRRKA RWIEYSPSDR RGEVIEESF
//
