ID U4L5F5_PYROM Unreviewed; 629 AA.
AC U4L5F5;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Similar to E3 ubiquitin-protein ligase itt1 acc. no. Q9US46 {ECO:0000313|EMBL:CCX07671.1};
GN ORFNames=PCON_07260 {ECO:0000313|EMBL:CCX07671.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX07671.1};
RN [1] {ECO:0000313|EMBL:CCX07671.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX07671.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX07671.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HF935360; CCX07671.1; -; Genomic_DNA.
DR AlphaFoldDB; U4L5F5; -.
DR STRING; 1076935.U4L5F5; -.
DR eggNOG; KOG1814; Eukaryota.
DR OMA; PRSWCQG; -.
DR OrthoDB; 4338126at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20354; Rcat_RBR_RNF14; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR047548; Rcat_RBR_RNF14.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF457; TRANSLATION TERMINATION INHIBITOR PROTEIN ITT1; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00591; RWD; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 18..133
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 164..453
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 168..213
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 227..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..258
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 68949 MW; A7E6D73426200297 CRC64;
MTSLSLETLS LSDDERSQEL FTIASIYPDE ITLLSPFSAS LVLPVIPLSP LTLQFASSPP
LQLRYLPPIK AIFDLPESYP ASEPPRIEII TQPEWLPENI LQELKKECDE LWEEGMQTVY
AVVDNIQQFT EGGFGGSKMV LPDELREEMV KFDQDAQREV FAKGTYDCGI CLEPKKGAQC
HALRSCTHVF CKACLVDWYS GAITEGDVSA VRCSDPVCVK AATRQAAQLD APPTPPPEGV
DAPAPPKPTI QPLPPTIPPE ELEEIGIPTD LVTRYVLLKK KKALEKDPHT IYCPRKWCQN
PSKSSIERVE SNMKQNGGGY WLPDFNAVKE EPIKENNNGK EDTASVKLDK LQICSVCAFA
FCRICRASWH GTLTICKPHD GTLTEEEIAN EKFLKENTTP CPTCNSPTLK SHGCNHMICA
CTTHFCFLCS AYLDASNPYT HFNTRGTECY QRLWEGEEGD EENIRRIRAA EEQREQEMDN
YEVVELAPAA AARPAQPAPV EPAPQQEEEI HEAQLIHPLG EEVVMDEDGI VWIDGQPFEV
VWTDDEDSDA EPENQIAFED APDEELGPVA RRGGRGGAPA RGGGRGRGNA RGGQGGGRGG
GRGGGQAARG GGRGGAQQAA ARGRGRGRP
//
