ID U4LHE6_PYROM Unreviewed; 547 AA.
AC U4LHE6;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Similar to Uracil permease acc. no. Q10279 {ECO:0000313|EMBL:CCX31549.1};
GN ORFNames=PCON_10898 {ECO:0000313|EMBL:CCX31549.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX31549.1};
RN [1] {ECO:0000313|EMBL:CCX31549.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX31549.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX31549.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; HF935604; CCX31549.1; -; Genomic_DNA.
DR AlphaFoldDB; U4LHE6; -.
DR STRING; 1076935.U4LHE6; -.
DR eggNOG; KOG2466; Eukaryota.
DR OMA; CIPTYML; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618:SF2; ALLANTOIN PERMEASE-RELATED; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 75..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 547 AA; 60379 MW; 317D1739E88135FA CRC64;
MSSFLRKLET DNEPGLNAAQ LMLTNHDLKP VEPSRRQWGP WNFVGFWIAD SFNINTWMIS
SSMILAGLSW WQSWLCVWIG YFIAAIFICA TGHIGATYHI GFPVVARSSF GIWGSLWPVF
NRAAMACVWY GVQAWIGGNC VYLMVRSIWN SFDDVPNTMG GAGTETKYFV SFLLFWFCSL
PAIWFPVHTI RHLFTVKAYI VPVAGFAFFG WCIHRAGGVG PIVSQPSSKQ GSELAWAFVG
GVMSSVSNFA TLIVNDPDFS RFAGKPTDQL WSQMFGIPCS FAFTSFVGII VSSSSTVIFG
KPIWNPLDLL AEFLDEGGSG NRAGVFFIAT AFSLAQLGTN IAANSVSAGS DMTALLPRYI
DIRRGGYVCA LVGLAMCPWN LLSSSNNFTL YLSSYSVFLS SIAGVMLSDY YFVRKGYLEI
KNLYSAKKNA PYYFTYGIHW RAYAAYIAGI LINVVGFAGA IGKTVPVGAT YIYRLNFFAG
VIVSSGTYWL LATFFPIPAC SDKWMEVGED ISEVRLAYDS SSDSYDIEAT DPKTEDGGVQ
EKFCRAY
//
