ID U4LJL3_PYROM Unreviewed; 638 AA.
AC U4LJL3;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000256|RuleBase:RU367076};
DE Short=RNA polymerase III subunit C3 {ECO:0000256|RuleBase:RU367076};
GN ORFNames=PCON_05636 {ECO:0000313|EMBL:CCX29565.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX29565.1};
RN [1] {ECO:0000313|EMBL:CCX29565.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX29565.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX29565.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific core component of RNA polymerase III which synthesizes small
CC RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|ARBA:ARBA00025127,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits. {ECO:0000256|ARBA:ARBA00011206,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000256|ARBA:ARBA00006835, ECO:0000256|RuleBase:RU367076}.
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DR EMBL; HF935279; CCX29565.1; -; Genomic_DNA.
DR AlphaFoldDB; U4LJL3; -.
DR STRING; 1076935.U4LJL3; -.
DR eggNOG; KOG2587; Eukaryota.
DR OMA; KHRFVRH; -.
DR OrthoDB; 1429291at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR InterPro; IPR039748; RPC3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12949:SF0; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3; 1.
DR PANTHER; PTHR12949; RNA POLYMERASE III DNA DIRECTED -RELATED; 1.
DR Pfam; PF08221; HTH_9; 1.
DR Pfam; PF05645; RNA_pol_Rpc82; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU367076}; Nucleus {ECO:0000256|RuleBase:RU367076};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367076}.
FT DOMAIN 10..66
FT /note="RNA polymerase III subunit RPC82-related helix-turn-
FT helix"
FT /evidence="ECO:0000259|Pfam:PF08221"
FT DOMAIN 166..467
FT /note="RNA polymerase III Rpc82 C -terminal"
FT /evidence="ECO:0000259|Pfam:PF05645"
FT REGION 359..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..401
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..419
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 73665 MW; 82BE4C8019DE22E5 CRC64;
MSQTSASAAE LCTLLVRDIY GEVSSKVVNV LLQRGRLTIG SIIQQTQLPP KSVKQTLVVL
IQQHLVVHYS HMEGGNDVCY YECNWEQAYE LLHAGRIIRA VEDYFGQDGA LIASNFLQLG
HVKVSDFLAA YGVSTKKTTK KAPNADTIAI EADAPITSVE TLKEVMMNML KARFLVEVKK
EDMQPQTDVE NNLRNELRKQ LASGFSSELK LNNEVNAKLK IKLKEMQIGD VSETAGLKRK
AAPAGGRVKK RKKVSIYDEE EEEIDYEIDE DLVLRINHDK FLVLFRNAEL VALAEQRIGK
VTSEVYREFL KRIEPKIFRC RDNFDEDEDD DDNDKIGVKK IKLSCLELSK HFDPEIELEG
SIALPPKETK TKKKRSYDSD DEEKPRKNGK TNGKSKHDSD SEEEEEESEA EDDWDNDADM
DPEAAKRKNR MKMIKQHLLL LAEDSFKFLS SEGNRGMGEW SVNYKELGKT MRAVEMEKIV
EERFESTGTR LLRIIKDKGK LDEKTISNIA LLKQGEVRSV LAQMQECGHL EVQEVPRANP
LQVNKTFFFW YFHEERANTL LLSDIYKAMS RNIQRTNVER QKRKHLIEKS ERSDVQANFE
EYMTKSEKRE LEIWRSREER LLVQLMRLDR LVMILRDF
//
