ID U4LKS2_PYROM Unreviewed; 365 AA.
AC U4LKS2;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Similar to DNA repair protein rad13 acc. no. P28706 {ECO:0000313|EMBL:CCX29960.1};
GN ORFNames=PCON_07757 {ECO:0000313|EMBL:CCX29960.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX29960.1};
RN [1] {ECO:0000313|EMBL:CCX29960.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX29960.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX29960.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HF935393; CCX29960.1; -; Genomic_DNA.
DR AlphaFoldDB; U4LKS2; -.
DR STRING; 1076935.U4LKS2; -.
DR eggNOG; KOG2520; Eukaryota.
DR OrthoDB; 5479162at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR CDD; cd09904; H3TH_XPG; 1.
DR CDD; cd09868; PIN_XPG_RAD2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR PANTHER; PTHR16171:SF7; DNA EXCISION REPAIR PROTEIN ERCC-5; 1.
DR PANTHER; PTHR16171; DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED; 1.
DR Pfam; PF00867; XPG_I; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 1..59
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 273..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..332
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..365
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 40163 MW; 006722CA28F17704 CRC64;
MEAEAQCAEL VKLGLVDGIV TDDSDVFLFG GTRVYRHMFN DRHTVQCYLA SDFEKEFSLD
QHRLIAAAQL LGSDYTEGVP SVGPVTAIEL LAEFAGDGGL TGFKAWWTKV QSGIDIPEES
STRFRKRFKR QNVAKVFLPP TFPNPAVEDA YLHPEVNSDP SAFEWGVPDL DGLREFLMNT
VGWSKERTND ILLPVVKDMN KKIQEGTQAN ITNFFTGAVG AGGFAPRVKA VGGSKRMEMA
MEKLKGADGN TETADKAEEY PVRKIMSMNE RFAQEAQEQT DEPTGAEKPK TKKRKAPAKG
RKKKATPALE PEDEDGESDY GSDIDIAELE GLEGMGEEGP PKKKGRKTAV TKRKAPAKRG
RKTAK
//
