ID U4LQG1_PYROM Unreviewed; 992 AA.
AC U4LQG1;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Similar to Tyrosine-protein phosphatase non-receptor type 1 acc. no. O13016 {ECO:0000313|EMBL:CCX31580.1};
GN ORFNames=PCON_11021 {ECO:0000313|EMBL:CCX31580.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX31580.1};
RN [1] {ECO:0000313|EMBL:CCX31580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX31580.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX31580.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class subfamily. {ECO:0000256|ARBA:ARBA00009649}.
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DR EMBL; HF935615; CCX31580.1; -; Genomic_DNA.
DR AlphaFoldDB; U4LQG1; -.
DR STRING; 1076935.U4LQG1; -.
DR eggNOG; KOG0789; Eukaryota.
DR OrthoDB; 1342035at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd01446; DSP_MapKP; 1.
DR CDD; cd18533; PTP_fungal; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR19134:SF551; TYROSINE-PROTEIN PHOSPHATASE 3; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 3: Inferred from homology;
KW Receptor {ECO:0000313|EMBL:CCX31580.1}.
FT DOMAIN 240..358
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 498..725
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 673..718
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..914
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 992 AA; 106809 MW; ECCA69F18EED6D56 CRC64;
MSGLTASTRK SNTTEAPSHN SHSQVRQFHT GPTSSQQQPT FDFPSPQVAL SNATETPAEN
PSAAGGYFNF VNDDPGLGNH STKNWSPASS SIRSAAARSP LPVLVDNPTT PFQIQTEVLA
RKLQRKDAPR LDLGSIRSNH TTAFAPASNT VPNLDTLTPQ GNDYFSSVRD SSPDRIDIGD
NDPWPPLSAP PSLRATPALP SPISMKLPAA RSMTLPIPAK DNNTNMIEPA QLSELITQHN
TDSLLLLDVR TYKNYSEARI KSAVNLCIPT TLLKRPSFNV TKLSETFANN QDKERFGQWK
KMKFIVVYDA DSNNLNDSSA LTALHTLNKF SREGWDGLPY ILKGGFSGFA AIFDNQVDRT
PPPKATTPVK GGLSLNGASG PEKVTGGVFN CPLPQSQSVV NPFFSNIRQN MDLIDGVGEI
PIQVPTTMSN KNLSQLPTWL NDVACKEDGS KVVADRFLKI EKAEQRRMQD ALNVSVVYDS
PTSASVRPHT LAGVEKGNKN RYNNIWPYDH SRVKLQEYPT DECDYVNASH ISVPHSQKRY
IASQAPLPST FRDFWSMIWE QDVRVIVMLT AESEGGRLKS HNYWNSDQYG SLKLTRIQER
KVSLEPPALK ASPKRRSVSC SSSQVANDIP YITVRKFTLE HTGCPFMPMR EITQLQYTGW
PDLGAPAHPS HVLGLVEHTD AVVRASSTSS EHPSRRPVLV HCSAGCGRTG TFCTVDSVIG
MMKRQMMHKR MLAKASGANG SAASSAASSA HSNYAPSVSP GSIAPATING SSQTNGSVNG
SSQPNGSATN GTASAPLAHP GAVNGASGIL SPNATTAALA QNSGPFFPMT STNHTTTAGA
SNSPFFSAAP APQSSTTPFF SPTGVVNHQS AISALPPPSA SQGFQLNLPG ALSPSQQASQ
QASQASQASH LPETSDHGLN LGMGMGTLGL EDDGDWIGRE DEDLVYKAVC ELRDQRISMV
QCLQQYVLCY ETVLEWLAKE QSSGEMGGKR KA
//
