ID U4LT07_PYROM Unreviewed; 960 AA.
AC U4LT07;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Similar to Rho guanine nucleotide exchange factor scd1 acc. no. P40995 {ECO:0000313|EMBL:CCX30511.1};
GN ORFNames=PCON_08710 {ECO:0000313|EMBL:CCX30511.1};
OS Pyronema omphalodes (strain CBS 100304) (Pyronema confluens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Pyronemataceae; Pyronema.
OX NCBI_TaxID=1076935 {ECO:0000313|EMBL:CCX30511.1};
RN [1] {ECO:0000313|EMBL:CCX30511.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS100304 {ECO:0000313|EMBL:CCX30511.1};
RC TISSUE=Vegetative mycelium {ECO:0000313|EMBL:CCX30511.1};
RX PubMed=24068976; DOI=10.1371/journal.pgen.1003820;
RA Traeger S., Altegoer F., Freitag M., Gabaldon T., Kempken F., Kumar A.,
RA Marcet-Houben M., Poggeler S., Stajich J.E., Nowrousian M.;
RT "The genome and development-dependent transcriptomes of Pyronema confluens:
RT a window into fungal evolution.";
RL PLoS Genet. 9:E1003820-E1003820(2013).
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DR EMBL; HF935441; CCX30511.1; -; Genomic_DNA.
DR AlphaFoldDB; U4LT07; -.
DR STRING; 1076935.U4LT07; -.
DR eggNOG; KOG3519; Eukaryota.
DR OMA; QPIYPRQ; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000018144; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
FT DOMAIN 219..391
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 867..956
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 578..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 828..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 960 AA; 106658 MW; 2DF24105F61BF08C CRC64;
MTVESEQDIF LRHSVASAPR TMTTIGTPAA VPNGANNVGS PTVTVMGIPQ ANDNIINKKA
DPAQGLFQTC LTLRQRLQDV PGFEKFLEPP EDADPNIPED PVTQLWRCFR LGSSLCALFN
ATQPKDAIRE DRLSPNLKTM NDCKAATFHF LKGIKTELDI QGEDAFMIHN LYSDDTNGFV
KVTKTVTKIL DILKERDLLI VRDDADQNAD NGEKKPLDNR ARIVKELVDT ERKYVQDLEA
LQDYMRCLER EEVVSKDLIH NLFLNLNQLV DFQRRFLIRV ETQNSLSEEQ QNWGHLFVQY
EKSFTVYEPY ASNFNGAQHL AQEAREQLAR MPHPVFDQLA AFLIKPVQRV TKYPLLLRDL
IKQTPPVEAM EKELPLGLAA IERITSAINE AIRKSENIEI VKDLEGRVED WKGHKLEHFG
ELLLHGQFSV IKGDQKGDVE REYYIYLFER ILLCCKEMGV GKKQNKTMSM GKSAKPPPGG
KKRTSLQLKG RIFMQNVTDV VSIARNGSYT LQIFWKGDPG VENFMIKHTN EEGLTHWKKI
LQKQRETFTK NEASTTGRQS GQSTASTQFA WMGITNNDPE VESRNASDDD DDATIIQDQD
RYSALSGTTL SSSRNGSMTN LRSRSATNEN MPPPNGAYMR GPTSNPPARF PIVPNGHTPP
LTLNTNPLYQ NLANSPERSN ASYFSPVETP MLTSRSSSAS GQAYPFPRYP QSQYYDESGP
QQFSPPSMSR SSSREGSSGT QQYTAFQSSA TAYANSSRLQ RPSLPGMGTS VPSISGLTQH
QSRMRSASSP NIHHIPGAAS QLSRVSPGGN IPPIPTIPTS VPGSYIPYSG GPAVIQRQNS
DSPTSPGLPI QGPRAETPTG DGSMNGVQQV KVKVHSNTDL FVLVVPYNIA YAQLIDRIER
KVEFCGALPA TPIRVRYQDE DGDYISMNSD DDVQMAFDAG CENVDPNQGG LTVTLYLQLG
//
