ID U4T791_9GAMM Unreviewed; 726 AA.
AC U4T791;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=M917_1071 {ECO:0000313|EMBL:ERL56011.1};
OS Psychrobacter aquaticus CMS 56.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Psychrobacter.
OX NCBI_TaxID=1354303 {ECO:0000313|EMBL:ERL56011.1, ECO:0000313|Proteomes:UP000016761};
RN [1] {ECO:0000313|EMBL:ERL56011.1, ECO:0000313|Proteomes:UP000016761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMS 56 {ECO:0000313|EMBL:ERL56011.1,
RC ECO:0000313|Proteomes:UP000016761};
RX PubMed=24201199;
RA Reddy G.S., Ara S., Singh A., Kumar Pinnaka A., Shivaji S.;
RT "Draft Genome Sequence of Psychrobacter aquaticus Strain CMS 56T, Isolated
RT from a Cyanobacterial Mat Sample Collected from Water Bodies in the McMurdo
RT Dry Valley Region of Antarctica.";
RL Genome Announc. 1:e00918-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL56011.1}.
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DR EMBL; AUSW01000016; ERL56011.1; -; Genomic_DNA.
DR RefSeq; WP_021813718.1; NZ_AUSW01000016.1.
DR AlphaFoldDB; U4T791; -.
DR STRING; 1354303.M917_1071; -.
DR PATRIC; fig|1354303.4.peg.1054; -.
DR eggNOG; COG0642; Bacteria.
DR eggNOG; COG3852; Bacteria.
DR OrthoDB; 9804645at2; -.
DR Proteomes; UP000016761; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF15; SENSOR HISTIDINE KINASE CRDS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ERL56011.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ERL56011.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 13..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..242
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 650..718
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 447..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 726 AA; 80455 MW; 16017D91421E0C17 CRC64;
MQQLGFRSVF AKLFASVMLA LILFAVAMVL LTQLVHDKDA GIRSEVLATQ ILGQIDPFLH
ELNISVSKDN RLQSRFMLAV VKKSFDIFDE SLQAKMGLYD SEGRLLMQTD NSDLPLELPE
PPSLLSRVFP SFTDTPPTKQ AQVYSSTGYT LLYESRLPPK KPVLSAALNL FTGTLLLLMI
MAGVLWWIAR TITWRINQMS QQMTQLGDGD FTVRVNARGN DEIASLARGF NQAAQKIEHL
IDANNLLLAH ASHELRTPIT RIRLQIEMMD MLTGALPADT KAKFDKRAQA INRDLSGLND
LVESILLVSR LDAGHALQQV ESLDLYHLVN QERQHYPEAT LIGEHIVIDG QSSMLTHLIR
NLLTNAMLHG KPPVTVLLYG VQTVDEANTV PDYLLQTVLC HSFADYNSSD FIYDEQSNIN
EDVSQHLLSL DESATSNTID NVKFEKTDST PLLPAPPIYK NGESMATNGD NEGDARLDSD
TRTDAESPTS VISPISTSPN TPKDLDAVQK SEKSSAIYET TSHEATGTSS LLANYYSFTT
DLTDRIKKVM WKAVPDSEAS NHSESAVTGD MTPKPKTRMI SGNISARKND EAHITDKTMV
DSTVIKNESK ANVQNEIETA STPRKESLFA KHIKKAKAEP VRPLPKYAVL AVIDEGTGIP
EDKREEVFSP FVRLQQKNKG SGLGLSLVSQ IVTAHQGRIL TDTLNGHTRF LVVIPVKHDP
HYHQHD
//
