ID U4TNI0_9LACO Unreviewed; 602 AA.
AC U4TNI0;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN Name=uidA {ECO:0000313|EMBL:ERL64985.1};
GN ORFNames=L248_3147 {ECO:0000313|EMBL:ERL64985.1};
OS Schleiferilactobacillus shenzhenensis LY-73.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1231336 {ECO:0000313|EMBL:ERL64985.1, ECO:0000313|Proteomes:UP000030647};
RN [1] {ECO:0000313|Proteomes:UP000030647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LY-73 {ECO:0000313|Proteomes:UP000030647};
RX PubMed=24265500;
RA Lin Z., Liu Z., Yang R., Zou Y., Wan D., Chen J., Guo M., Zhao J., Fang C.,
RA Yang R., Liu F.;
RT "Whole-Genome Sequencing of Lactobacillus shenzhenensis Strain LY-73T.";
RL Genome Announc. 1:e00972-e00913(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
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DR EMBL; KI271590; ERL64985.1; -; Genomic_DNA.
DR RefSeq; WP_022529732.1; NZ_KI271590.1.
DR AlphaFoldDB; U4TNI0; -.
DR STRING; 1231336.L248_3147; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_006501_6_1_9; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000030647; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154}.
FT DOMAIN 17..183
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 186..276
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 278..593
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 602 AA; 67573 MW; A1D607460AD152BB CRC64;
MEKEMLYPVI NACRTEQKLD GMWQFKFDAL GVGGHEHWPA GLPQAQEIPV PASFNDFFTD
KDSREYTGDF WYARHFFVPA AAQGRFVGLR FDAVTHRAAI YVNGQLIRRH EGGFLPFVAD
VTAAVHYGAD NLVVVQGNNE LSREALPAGD TVTLKNGKKM ARPFFDFYNY SGINRSVHLL
TLPQQRITDY TVNTTLTGDA AQVAYTVATT VPGTVTVTLT DAAGTVVAQG EGAEGTLTVA
QPHLWQVRAA YLYTLTIQLQ AAGQLVDEYQ DSIGLRTIAI RGHQILVNGQ PVYLKGFGRH
EDSPFAGRGF DQNVEAKDVA LMAWTGANSF RTAHYPYAEE VYQMADRAGF LVIDEVPAVG
FKMAAASFLG GLDQSFFGGD WIKPLYTKHL DQITDMIRRD KNHPAVLAWS LLNEPDTCDD
RSVPYFKQLF ADTAALDPQR RPRTFTLSED DTITTSKDLQ FPDFYLLNRY PGWYHYAGYA
LSDGEAALRA ELDQWASSGI DKPIVFSEFG ADTEAGLHKL PSVMWSEEYQ VEVLQMFSRV
FDSYPFIRGE QVWNFADFQT VEGTMRVNGN KKGIFTRDRQ PKAAAFYYRQ RWLALPLNFK
ND
//
