ID U4U2U8_DENPD Unreviewed; 468 AA.
AC U4U2U8;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Origin recognition complex subunit 5 {ECO:0008006|Google:ProtNLM};
GN ORFNames=D910_04064 {ECO:0000313|EMBL:ERL86658.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL86658.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL86658.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC5 family.
CC {ECO:0000256|ARBA:ARBA00006269}.
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DR EMBL; KB631843; ERL86658.1; -; Genomic_DNA.
DR AlphaFoldDB; U4U2U8; -.
DR STRING; 77166.U4U2U8; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR020796; ORC5.
DR InterPro; IPR047088; ORC5_C.
DR InterPro; IPR048866; ORC5_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12705; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR12705:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF14630; ORC5_C; 1.
DR Pfam; PF21639; ORC5_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 54..192
FT /note="Orc1-like AAA ATPase"
FT /evidence="ECO:0000259|Pfam:PF13191"
FT DOMAIN 251..309
FT /note="ORC5 lid"
FT /evidence="ECO:0000259|Pfam:PF21639"
FT DOMAIN 329..462
FT /note="Origin recognition complex subunit 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14630"
SQ SEQUENCE 468 AA; 52998 MW; AC582DAAAE24FD46 CRC64;
MVSAFFGGNT KCFNGFFVLR GRVAAQGGQP PCWNRRPADI TSQTHQMDAL SKSFPGREPQ
IAQLLAYFRA APYPPAVYIR GGPSSGKCAI VSGLLGALRI RHALVDLVEC YSSKVLFELV
LNQLSGHRVD PAVGAPFAAC DHLMDFVGQL GRIEGLDGSV VVLRHAEELR KMEANVLAGF
LGLRQLTRVR VSVVLLSEVA FEKYYHKLNL SEPLKVHFPQ YSMEQLLDIL QLDFPHAEQL
SAVQVDREFH RSYLSVFLPV FYRACRDLSE LRHMSRKHFA QYCQPVLDQQ LRAQDSLALW
KRIAPIFNAA TSVLYLRVSS KHPGQGLELP FYSKYLLIAA YLASYNSSTD DKRLFMKFHG
KKRKTRHDIE RKNKPSAHLN TQIGPKAFTL DRLLAIFYSI LEDKVGFNNH LLIQVSSLVQ
LQLLSLASDE CSLDERKYKC NVNFETIQTI ARMVGFNVRK FLTDFSHM
//
