ID U4U334_DENPD Unreviewed; 558 AA.
AC U4U334;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
DE Flags: Fragment;
GN ORFNames=D910_05691 {ECO:0000313|EMBL:ERL88304.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL88304.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL88304.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KB632050; ERL88304.1; -; Genomic_DNA.
DR AlphaFoldDB; U4U334; -.
DR SMR; U4U334; -.
DR STRING; 77166.U4U334; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06892; PX_SNX5_like; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.20.120.1250; Sulfhydryl oxidase R596, ORFan domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR45850:SF1; SORTING NEXIN 6, ISOFORM B; 1.
DR PANTHER; PTHR45850; SORTING NEXIN FAMILY MEMBER; 1.
DR Pfam; PF00787; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 253..400
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 204..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 558
FT /evidence="ECO:0000313|EMBL:ERL88304.1"
SQ SEQUENCE 558 AA; 64177 MW; 4A8506C460860BBD CRC64;
MSDKPDTVPG LGFKDQEKAQ ETLKNLEGRD PDYQKLAIKG LIGRAKRTLT LTKDKDKLQN
ITDAISVFEQ WLKDFESNNL AKENRPYLPV LSVKALLPLK DKYELKDELA ERFLKAYSEE
AKGEYKNLRT ISSGDGEPTW DIVRNKQLKT IPTSSIDLWD DQDLPTKEHM ELVLWAYSPE
ASKIKKNVSN YEEKLGNLKI ASDEEEAKEE KKGRKRKSEG SSSSSQSEES NASEDDESPK
KKSKKAEEDK MVPLTDNSLV VDISDALSEK DKVKFTVHTR TTMNNFQKLE FLVVRQHEEF
IWLHDRFEEE PKYAGYIIPP PPPRPNFDAS REKLQRLGEG EGTMTKEEFT KMKQELEAEY
LATFKKTVAM HEVFLTRLAC HSVFREDSHL HVFLEYDQDL CARPKGKLQQ LGGLVKSLGS
TTDQYYLNAT VRDVNDFFEQ QMVSLTEYHT QLRDATGRTD RMTEKHKELA DSYIKISSGL
LQLANSDNGH LDKFFARKVE SRVASDQDLK LADTLRYYMR DSQAAKSLLV RRLKCLANYE
NANRALEKAR HKNKDIHA
//
