ID   U4U4V0_DENPD            Unreviewed;      1208 AA.
AC   U4U4V0;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   13-SEP-2023, entry version 32.
DE   RecName: Full=RH1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=D910_03053 {ECO:0000313|EMBL:ERL85636.1};
OS   Dendroctonus ponderosae (Mountain pine beetle).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC   Curculionidae; Scolytinae; Dendroctonus.
OX   NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL85636.1, ECO:0000313|Proteomes:UP000030742};
RN   [1] {ECO:0000313|EMBL:ERL85636.1, ECO:0000313|Proteomes:UP000030742}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA   Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA   Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA   Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA   Birol I., Jones S.J., Bohlmann J.;
RT   "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT   a major forest pest.";
RL   Genome Biol. 14:R27-R27(2013).
CC   -!- SIMILARITY: Belongs to the JIP scaffold family.
CC       {ECO:0000256|ARBA:ARBA00009866}.
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DR   EMBL; KB631730; ERL85636.1; -; Genomic_DNA.
DR   AlphaFoldDB; U4U4V0; -.
DR   STRING; 77166.U4U4V0; -.
DR   Proteomes; UP000030742; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR   Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR039911; JIP3/JIP4.
DR   InterPro; IPR032486; JIP_LZII.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR13886:SF4; JNK-INTERACTING PROTEIN 3; 1.
DR   PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF16471; JIP_LZII; 1.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF19056; WD40_2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT   DOMAIN          6..94
FT                   /note="RH1"
FT                   /evidence="ECO:0000259|PROSITE:PS51776"
FT   DOMAIN          432..502
FT                   /note="RH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51777"
FT   REGION          260..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          729..774
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          807..831
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1137..1164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          60..161
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          366..460
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        264..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        729..757
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        807..827
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1138..1164
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1208 AA;  135070 MW;  CFC94904D2A88C00 CRC64;
     MSIGAEVVYG THEESHVVMS EKVQALAGSI YQEFERMISQ YDEDVVKTLL PLLVNVLECL
     DSAYQQNQEQ DVEVELLKED NEQLVTQYER EKGARKTAEQ KLLEYEDAAE GERKELTSRL
     ESLESIVRML ELKHKNSMEH ANRLEEREGE LKKEYAKLHE RYTELFKTHV DYMERTKLLH
     SGQQLVNERV EAGRLNSNRL NMGRSSGPIS FGFASLEDAE NVSLPVMYPE TVLQFGKISL
     HNEMDSLSRK PVLKVERAQE TDTINLENKS VVTSPVSPTS HPNSSGGGRL HTKREQRSGN
     TLYQELSFQD VDGDEDPTDI TGGWVHPGEY ASSVNDNFYG MGKEVENLIM ENNELMATKN
     ALNVVKDDLI VKVDELTGEI DMLREEILSL NVSRTKLRER TTELEEELRK VKEAHEAKQD
     GDEEEDVPMA ERKRFTRLEM SRVLMEKNQY KENLMELQEA VRWAQIIKAS REPSLDKHSN
     RSIWSFFSNL FSGGDRVQRS MMGPDFRYQA ATNRVSPGLR SLARIQDRSD VEMGSEKFAI
     RKAMERREQY RQVRAHVKKD DGRLHAYGWS LPGKVVATET TGKQSNSVPV PVPVYCRPLA
     ETKANMRIWC AAGVNSMGGY TKDGGLMVTN NIYLKLVCLI ITFVRLVIED LEKELNDCRE
     GALLETRLTS MVWIVTTTQH ASMVTVIDAN NPAELLTSFG VCSAHVLCIA SVPGASPSDY
     IDTPIEIPIE AHEDNPESNE ATNGEKEKEK ENNAHPSKVT ETPEGRAKAV QDGGVGTNTL
     RTQEANQEAA LLGKISFVEN DQTAVKTTNK ASCSVSDNDS KTDDNVAQGN PDKVLEENDA
     IENPKDPNQN PTHGYKSPTL NLETMSTVLA TMWLADTDGN VYIHSSVANW HRRLQTVKLG
     DSVISIVHVN GRVVVALANG QLAVFKRHSN GEWDLSQYHI VQIGLPHQSV RKLAVVGDKV
     WCGYRNKIHV LQPRELKIIH TLEAHPRRES PVRDMAWLGE GVWVSIRLDS TLRLYHAHTY
     QHLQDVDIEP YVSKMLGTGK LGFSFVRITS LLISSNRLWI GTSNGVIISV PLTDSCNCSS
     GSIISRGSSM SGSAIRFPRV AFPEHFVPYC TMAHAQLSFH GHRDNVKFFV AVPGKGGISS
     ASSPSEAMSA SVTSLESPTK QPPTSMLVIS GGEGYVDFRV EDDCEPRDGA SHLLIWQVIN
     IEPGNPMG
//