ID U4UAV6_DENPD Unreviewed; 258 AA.
AC U4UAV6;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Homeobox domain-containing protein {ECO:0000259|PROSITE:PS50071};
DE Flags: Fragment;
GN ORFNames=D910_04495 {ECO:0000313|EMBL:ERL87095.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL87095.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL87095.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/IRO homeobox family.
CC {ECO:0000256|ARBA:ARBA00008446}.
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DR EMBL; KB631904; ERL87095.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UAV6; -.
DR STRING; 77166.U4UAV6; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:UniProt.
DR GO; GO:0001654; P:eye development; IEA:UniProt.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR PANTHER; PTHR11211:SF3; HOMEOBOX PROTEIN MOHAWK; 1.
DR PANTHER; PTHR11211; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 5..68
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 7..69
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ERL87095.1"
SQ SEQUENCE 258 AA; 30343 MW; 64BF7D3C23604A2C CRC64;
RVYGEERRPP KRLFTPEIKR FLKDWLIRRR DNPYPNRDEK KVLAVQTGLT YIQVCNWFAN
WRRKLKNAGK EPQRRTWGDL IKTYNSQVQG NVEHFSICSE DSIWEEPEGA YTNIELQRFE
EHYAKGQLDH SYGQLCNNNN NNNKSDQCYF VSSTTELDQD NPFSQSANKY KNHIMEKYMR
DCQSSGVVEA DKPAMIAKWL QSAERFRPNE GNYIDWSFNK PQKKKPAKVE TDLMLVHGKE
ELDAAEALTS LANSNRHK
//
