ID U4UFK8_DENPD Unreviewed; 907 AA.
AC U4UFK8;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
GN ORFNames=D910_06717 {ECO:0000313|EMBL:ERL89346.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL89346.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL89346.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
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DR EMBL; KB632168; ERL89346.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UFK8; -.
DR STRING; 77166.U4UFK8; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 487..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 719..741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 153..185
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 223..256
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 258..290
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 291..315
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 325..361
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 362..394
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 565..751
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 824..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 863..897
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 907 AA; 102339 MW; A6BD86108C77E2BC CRC64;
MQIRLRIDGH LFPGFPSTLS YDNATDIYES ITGFNPVSLN YDSIITSLDD LNRYKSSKFR
IPSEIEWHII GPEYVKDLFK DANDIEVNIG FLWAAFLKRA DLVGVFLELG ADLSFHEPNY
GLTALHLAAF AGCKSTTEFL LSQKECYVNL MYKCYSPLHC AAFGNNPEIA SILLEAGANI
DAISNDLQNN LEGVLHCAVR SKAVDCLELL CTKGANVNQL DSCGRTAIHL AAELGSAECL
RILVQAKGAN IDYQTKEKQH TALHVAAQQR HVNCVDVLLD YGALPNIVDY KHRTPLHLAA
KSQSNECVKL LLQKGKTNPN LPDANQRMPL HLSVAEPHQT INCVTMKTLL RFGADVNAKD
SKGCTPLHLA ATNELPKYVE TLILHNADIT ATCDGGVTAL GMIYRKTPAS MDTIRKKLDE
CIVLKSQDCS SRESELEVNF TPILQHCYPN EIEFLKTLLV EGQKELLLHP VCRAFLHLKW
KKIRKIFVFR AIWSFLLVLL MSSFVLMGLA KHCYNVSKNI TLTTYDLDRD LCINHSFAGS
FIVAHPFILE LQWYLMLILA LAIVVRKLCA ISAYSSFIQY FRSMQNLLDW STVVVVFLIS
FIYTGRTYIW QNHVCAFGVL IVWYNFFYLL GQFPFFGTYI AMYSSVQKEF LKLLLIFSCL
LMGFNVSFCV LFPNSQLFPN VYIGFITVLA MAIGEANLDL ITDPNKQDEI FMLRGSAQFI
YAIFITCVTI ILLNLLVGIA VHDIQGLKKT AKLTKLTKAT ELISCVDRAL FANYFDKIFL
PEVWRWSTLI STNGYYAVTV KIYNHQQGLL PSDIIHAAYE VARKHKKRNR SSKSHDQGKI
SMAPREQLSR KISSKNFANE VDVSGLQKDV RNLSNQVANM KEMLESHQRL MEQILRSVNA
GDKGIYF
//
