ID U4UGZ2_DENPD Unreviewed; 1175 AA.
AC U4UGZ2;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Bromo domain-containing protein {ECO:0000259|PROSITE:PS50014};
GN ORFNames=D910_09614 {ECO:0000313|EMBL:ERL92297.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL92297.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL92297.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
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DR EMBL; KB632319; ERL92297.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UGZ2; -.
DR STRING; 77166.U4UGZ2; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:UniProt.
DR GO; GO:0034641; P:cellular nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0046483; P:heterocycle metabolic process; IEA:UniProt.
DR GO; GO:1901360; P:organic cyclic compound metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR010286; METTL16/RlmF.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13393:SF0; RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16; 1.
DR PANTHER; PTHR13393; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF05971; Methyltransf_10; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 639..690
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 161..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 99..134
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 397..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1175 AA; 133851 MW; 7F1535D0A5AC5026 CRC64;
MNVSSIQERL QLKREPLDKW SVREQLCLAS AVSRSGDQNW MSVSRALKPF GDSNRPLDWF
HQKNCAAQYG ALLSHVETPK RKKRSGNETI METPVECILR RLLSERQNQL RELLAEEKAE
YNRLQDDMKQ MQSGDQKRKS PVDDFLEQEI GVSQYMNLQR PQKPSQFSAE IQQPPEPAKP
ALSPLLTSLL KSPSQVPIST SSILHTAITQ QSNKLPEVSS SHSSPTITSL LHSSAISFTQ
NQSDDCSQPL NADILDDNNL KIDDLAKSIL VQDGPFPEIK KEEVDDIISE IIENNHDIVS
DPEQHLQLDG NGDININLEL DELEQEETMK DASCPVKPEP PVEVPPVVDP FEFQEDPIMF
ESPVKTVKQE GQYLPLYQQS SPVKVEETDK VKATESAESR NNSLNPQSSF DVVTDKTVVE
EVQKIASDCP ISTDAAQYEE NDTKPISTQE NVSEKANVVE EDKECIAQTD APADEQPALE
TQEELKSSCC ELPKTDESSS ETTNLSQSET APEYEDDLYD NVNMEVKIDK TGKTKRDYSR
TKKRDDKNFD MLIGIEKPHL DNDDFSDKKE PVMVPLMKVD NERSNSPWAE EEDGNLKKRR
YSTPMDSMPN SPASSTAYDD DKDYRNWKKS MMLVYNRLAS NKYASLFFKP ITEEHAPGYR
AIVYRPMDLQ TIKKNIDTGV IRTSLEFKRD RFSSKKFFFY NILTYKMSMN KFMHPRNIYK
NPPNFKQLAV EFPEFKRHVR IDITGKVQFD FKDPEALRAL SHTLLLKDFH LDVCIPVNKL
VPTIPLRLNY ILWIEDLLDF IGRIDHVEGI DIGTGASCVY PLIAAQKNQW SMLATEADTG
SFEQAKQNIV SNGFQHLVKV VQVSKDIFLA GAVDADKVYD FCMCNPPFFA STQELHPFFK
ARTQNRPHPK NAFVASVHET VAKGGEVDFI QKMIAESTQL KTQIKLYTTM VGQKSSLPAL
KKCLREAKVH SFKVAEFCQG NTTRWGLAWT YLNHDLRKAS EEAKIATKSY KQRGPLLYDL
EGEQNTPENI VKITSMFLQL FKSLQMSCED VSRNKLHPRY FVTASSNTWS HQRRKLRAKL
RQGQLAESKT IDDPADSSAA KRSLDDLLCE STCKKLRLST DSESSDHAFY KFMFAINCLN
KKLILELNTL DNNVDREPLH QIMQFIKNNC RNLVN
//
