ID U4UQ80_DENPD Unreviewed; 786 AA.
AC U4UQ80;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=dynamin GTPase {ECO:0000256|ARBA:ARBA00011980};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
GN ORFNames=D910_09505 {ECO:0000313|EMBL:ERL92185.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ERL92185.1, ECO:0000313|Proteomes:UP000030742};
RN [1] {ECO:0000313|EMBL:ERL92185.1, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB632314; ERL92185.1; -; Genomic_DNA.
DR AlphaFoldDB; U4UQ80; -.
DR STRING; 77166.U4UQ80; -.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR CDD; cd01256; PH_dynamin; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF212; DYNAMIN; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW GTP-binding {ECO:0000256|RuleBase:RU003932};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003932};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 29..295
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 519..624
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 652..743
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 786 AA; 89353 MW; 0791D64D62775311 CRC64;
MSGISGMEQL INVVNKLQDA FTRLGVQLTV DLPQIAVVGG QSAGKSSVLE NFVGRDFLPR
GSGIVTRRPL ILQLVYSQYE YAEFLHKPGK KYMDFNEVRR EIEADTDRVT GKNKGISNLP
INLRVSSPNV LNLTLIDLPG MTKIAIGDQP PDIEVQIRNM ILEYIKRDSC LILAVTPANT
DLANSDALQI AKEVDPKGFR TIGVLTKLDL MDQGTDAKDV LENKLVPLRR GYVGVINRSQ
KDLDGGKDIK LQIKAERDYF LQHPSYKHMA DKMGTTYLQK TLNAQLTNHI HNTLPSLRDK
LQKQLYALEK NLGDMKHFKL DDKTMKTKAL LQMIQNFSLE FEKALEGSRS SEINTSELCG
GAKINSLFHE RFPFDIVKME FDENELRKEI GIAICNIHGI RIGLFTPDLA FDAIVKKQIA
RLKDPCLKCT DLVVAELLKI IHFCTERMAR YPVLRDTIER IISSQLSKSE VQCKEQISLY
IDFQLSYMNT NHEDFIGFAN AENQAEKNIS GTSNAPGNQV IRKGYMCIHN QSMIRGAKDY
WFVLTSDSLA WFKDDTEKEI QYILPLNGIK VKDLESKFIS RRHTFGLFYQ NGRNIYKDNK
QLELSCSSLD EEVTWKASFL RAGVYPERQK EANNNEDIEV KEEVDPQLKR QVEVIRNLVD
SYMGIINKST KDLIPKVITH MILNTTKKFI SEELLLHVYS TENQEGLMEE SPEEVRKREE
NMQMYQACKE ALSIIGECSV SFSSQMTRNE TYHPPKPPIA AKKIYRLSTP IQTVTRPAPP
PPPGTD
//
