ID U5CZS6_AMBTC Unreviewed; 450 AA.
AC U5CZS6;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CSC1/OSCA1-like N-terminal transmembrane domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMTR_s00038p00185310 {ECO:0000313|EMBL:ERN14627.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN14627.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KI392532; ERN14627.1; -; Genomic_DNA.
DR AlphaFoldDB; U5CZS6; -.
DR EnsemblPlants; ERN14627; ERN14627; AMTR_s00038p00185310.
DR Gramene; ERN14627; ERN14627; AMTR_s00038p00185310.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_608837_0_0_1; -.
DR OMA; RIITAMI; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IBA:GO_Central.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF5; OS01G0534900 PROTEIN; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..91
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 112..211
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 244..409
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 450 AA; 51802 MW; 3A8618326E0B091A CRC64;
MDHAKLDSAV YIRIYLVGLK LFVSITLLAF SVLVPVNWTE ATLEHQSLDL TFNKIDKLFV
SNIAYGSKRF WIQMTMAYAF TFWACYVLYK EYEIVASMRL LFLASEVRRP DQFMVIVRNV
PTDPDESVSE HVEPFFYVNH PNHSLTYQVA YNANKLARIV KKKKSLHNWL DYNQNNCARN
PSRRSTREGG FLGLWGESMD SIDFYTIDID KTRWAAVVCA QTQQSRNPTL WLTEWAPKPH
DCIFGNILKG TAFEQLKMCI NQSSDEIAKT IGVSIPMKAA FFKTYILVDD WSGVAAEILR
LKHLIMYHLS NTLLVNTEKD REDTLNPRSL GFTSPKPQLH SYFLLDLVYA IVTPIRRSFI
CLLWPDIYGL PILDLYNQEY ESVASFWPDI HGCTIIAMVI SQLVLMGLMS TRGAAQSTTI
LIPRPILTIW FHMVCKAGLN MHLSNFLYKK
//
