ID U5D1E0_AMBTC Unreviewed; 175 AA.
AC U5D1E0;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1 {ECO:0000256|ARBA:ARBA00013306, ECO:0000256|PIRNR:PIRNR008716};
GN ORFNames=AMTR_s00033p00027780 {ECO:0000313|EMBL:ERN14173.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN14173.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- FUNCTION: E1-like enzyme which specifically catalyzes the second step
CC in ufmylation. Ufmylation is involved in reticulophagy (also called ER-
CC phagy) induced in response to endoplasmic reticulum stress.
CC {ECO:0000256|PIRNR:PIRNR008716}.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC subfamily. {ECO:0000256|ARBA:ARBA00008451,
CC ECO:0000256|PIRNR:PIRNR008716}.
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DR EMBL; KI392557; ERN14173.1; -; Genomic_DNA.
DR RefSeq; XP_006852706.1; XM_006852644.2.
DR AlphaFoldDB; U5D1E0; -.
DR STRING; 13333.U5D1E0; -.
DR EnsemblPlants; ERN14173; ERN14173; AMTR_s00033p00027780.
DR GeneID; 18442431; -.
DR Gramene; ERN14173; ERN14173; AMTR_s00033p00027780.
DR KEGG; atr:18442431; -.
DR eggNOG; KOG3357; Eukaryota.
DR HOGENOM; CLU_101170_0_0_1; -.
DR OMA; PLWAKNV; -.
DR OrthoDB; 67279at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR GO; GO:0071568; F:UFM1 transferase activity; IBA:GO_Central.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR014806; Ufc1.
DR PANTHER; PTHR12921; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR PANTHER; PTHR12921:SF0; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR Pfam; PF08694; UFC1; 1.
DR PIRSF; PIRSF008716; DUF1782; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR008716}.
FT ACT_SITE 120
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR008716-1"
SQ SEQUENCE 175 AA; 19657 MW; 3345FE1DB90343B1 CRC64;
MATGGWDTTT KSTLSQIPLL KTRAGPRDGE AWTQRLKEEY AALIKYMTMN KSNDNDWFRI
SGSADGTRWT GKCWYIHNLL RYEFDLQFDI PVTYPATAPE IELPQLDGKT PKMYRGGKIC
LTVHFKPLWA KNCPRFGIAH ALCLGLAPWL AAEVPLLVDS GIIKHKDDTP SSVVS
//
