ID   U5D1U8_AMBTC            Unreviewed;      1229 AA.
AC   U5D1U8;
DT   11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=DNA-directed DNA polymerase family A palm domain-containing protein {ECO:0000259|SMART:SM00482};
GN   ORFNames=AMTR_s00062p00102370 {ECO:0000313|EMBL:ERN19576.1};
OS   Amborella trichopoda.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX   NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN19576.1, ECO:0000313|Proteomes:UP000017836};
RN   [1] {ECO:0000313|Proteomes:UP000017836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24357323;
RG   Amborella Genome Project;
RT   "The Amborella genome and the evolution of flowering plants.";
RL   Science 342:1241089-1241089(2013).
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DR   EMBL; KI392068; ERN19576.1; -; Genomic_DNA.
DR   RefSeq; XP_006858109.1; XM_006858047.2.
DR   AlphaFoldDB; U5D1U8; -.
DR   STRING; 13333.U5D1U8; -.
DR   EnsemblPlants; ERN19576; ERN19576; AMTR_s00062p00102370.
DR   GeneID; 18447964; -.
DR   Gramene; ERN19576; ERN19576; AMTR_s00062p00102370.
DR   KEGG; atr:18447964; -.
DR   eggNOG; KOG0950; Eukaryota.
DR   HOGENOM; CLU_004638_0_0_1; -.
DR   OMA; LASCKSM; -.
DR   OrthoDB; 208079at2759; -.
DR   Proteomes; UP000017836; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:GO_Central.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   GO; GO:0006302; P:double-strand break repair; IBA:GO_Central.
DR   CDD; cd08640; DNA_pol_A_plastid_like; 1.
DR   CDD; cd06139; DNA_polA_I_Ecoli_like_exo; 1.
DR   Gene3D; 3.30.70.370; -; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR002298; DNA_polymerase_A.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR   PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR   Pfam; PF00476; DNA_pol_A; 2.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   PRINTS; PR00868; DNAPOLI.
DR   SMART; SM00482; POLAc; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT   DOMAIN          959..1189
FT                   /note="DNA-directed DNA polymerase family A palm"
FT                   /evidence="ECO:0000259|SMART:SM00482"
FT   REGION          123..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1229 AA;  137021 MW;  B7EF25F118017A94 CRC64;
     MGLGVVTAQG VGGPFKPCCY CSPSFWFSSS SSSSSSTHFY RRVASVHSFA ASVKGFQRQE
     IGSFQEVDST YSNHSRLAPL KFRSVATLAS RSVILESQTG ILNDADGSSR VLDFEVRTNL
     RSSHSSSNRR LPYFTNGPDP RGERSRSTSL VNWQNTEDEH RQSLRSPINE PLITGTGRVP
     PFRTHNSGAS VDGINARWLE ESRKMRASRL GQQPSCNMSD GSVTAEISRS GTILQKEKND
     LVCLKGRTPH VKDPLRSTSF YGQKLEENHV VKSVLNTPYM RESMRGSMTN MRDDLFRLKN
     GNYYAQEGQM MSSNRPSYLE PTQNDLGVKN NCSFSVANSP VRTQMKEDAA VDLPTHLGVL
     RKQIEGEHAQ TNGSLIKKVV FQNSVVPYEF VEEISDDAMA EEILNGQAVN SESIDTFVEK
     VTTKTESNNA QAEQRKKLLC LYDKVLIVDN LSVAKSVVSK LTKEYRHLVH ACDTEVAKID
     VKGETPVGNG EVICFSIYSG EADFGNGKSC IWVDVLDGGR DMLMAFAPFF EDPAIKKVWH
     NYSFDNHVLE NYGFKVHGFH ADTIHLARLW DSSRRAEGGY SLEALTGDPK VMSGPGLTAK
     DELISGKISM KTIFGKRKVK KDGSEGKLVT LPPVEELQRK ERIPWICYSA LDSVSTLKLF
     VSLKGKLMAM GWVLDGVQRG TMYDFYEEYW RPFGEILVRM ESEGMLVDRC HLSKMEKIAI
     QEREIAVNRF RKWASQYCPD ALYMNVGSDS QLRLLFFGGM QNRKDPNETL PFEKTFKVPN
     VDEFIEEGKK APAKNRTIVL RSLGVEMHTE MYTPSGWPSV SGDALKAFAG KVSSIPYGAM
     DDNDENPVDS VLEEEEAKLN GKEASTSAEI DTSMYGSAYS AFGDGEKGRE ACHAIAALCE
     VCSIDSLISN FILPLQGDRI SCGNGRIHCS LNINTETGRL SARRPSLQNQ PALEKDRYKI
     RQAFIAAPGN SLIVADYGQL ELRILAHLSN CKSMLDAFKA GGDFHSRTAM NMYAHVCEAV
     EEKRVLLEWH PQPGEEKPPV PLLKDAFGSE RRKAKMLNFS IAYGKTPVGL SRDWKVSLKE
     AKETVNLWYK ERKEVLRWQE ERKSEAANKG CVHTLLGRAR RFPSMANASY SQRGHIERAA
     INTPVQGSAA DVAMCAMLEI SRNSRLKDLG WKLLLQVHDE VILEGPTDSA EEAKAIVVEC
     MSKPFYGTNF LKVDLSVDAN CEQNWYAAK
//