ID U5D688_AMBTC Unreviewed; 486 AA.
AC U5D688;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=BRCA1-associated protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMTR_s00046p00080660 {ECO:0000313|EMBL:ERN17959.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN17959.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI392290; ERN17959.1; -; Genomic_DNA.
DR RefSeq; XP_006856492.1; XM_006856430.2.
DR AlphaFoldDB; U5D688; -.
DR STRING; 13333.U5D688; -.
DR EnsemblPlants; ERN17959; ERN17959; AMTR_s00046p00080660.
DR GeneID; 18446308; -.
DR Gramene; ERN17959; ERN17959; AMTR_s00046p00080660.
DR KEGG; atr:18446308; -.
DR eggNOG; KOG0804; Eukaryota.
DR HOGENOM; CLU_009969_1_0_1; -.
DR OMA; CNADSDM; -.
DR OrthoDB; 123540at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:EnsemblPlants.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0007265; P:Ras protein signal transduction; IBA:GO_Central.
DR GO; GO:0010029; P:regulation of seed germination; IEA:EnsemblPlants.
DR CDD; cd16457; RING-H2_BRAP2; 1.
DR CDD; cd12437; RRM_BRAP2_like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR011422; BRAP2/ETP1_RRM.
DR InterPro; IPR047243; RING-H2_BRAP2.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR24007:SF10; BRAP2 RING ZNF UBP DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24007; BRCA1-ASSOCIATED PROTEIN; 1.
DR Pfam; PF07576; BRAP2; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 173..213
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 207..300
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT REGION 451..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 55243 MW; 7B6D2F7A735C75BD CRC64;
MFTLSIHSVE IPFSTTKYGD ASSSPTSTHS LFFFSGNPRF QESKGIIHLF RNVSDLPASP
DALPEGRSTL VCVLAVPNHI TYAEFFQFSG SFAEHMLEMR VIRNDGMDDR YSVLVMFENQ
NSTDGFFRHC NGRRFSSVEA EVCHVLFTSD VRYTDSIEIA ETPPKGLTEL PTCPVCLERL
DQDISGILTT MCNHSFHGSC TAKWTNSSCP VCRFCQQQPE KSSCSICETL ENLWICIICG
FVGCGRYKEG HAIRHWKETQ HCYSLDLENQ RVWDYVGDKH VHRLIQSKTD GKLVELNSHC
GSVDDECGSC EYSGDSGVSA ALFNSKFEAI VDEYNHLLAN QLESQRQYYE SLLVETKEQK
DRTVSAAARE AVNLKLQEMH VKLDKCSAEN RGIADANDKL MKKQEIWKKK LQEIEEREKM
AIKERDEKIM DLEEQVRDFM VYIEAQKTLD NLPNTDDVKG GTLLPVSVQS PSTNTKHTTK
TNRRRR
//
