ID U5E5V7_NOCAS Unreviewed; 706 AA.
AC U5E5V7;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=NCAST_05_00820 {ECO:0000313|EMBL:GAD81648.1};
OS Nocardia asteroides NBRC 15531.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1110697 {ECO:0000313|EMBL:GAD81648.1, ECO:0000313|Proteomes:UP000017048};
RN [1] {ECO:0000313|EMBL:GAD81648.1, ECO:0000313|Proteomes:UP000017048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15531 {ECO:0000313|EMBL:GAD81648.1,
RC ECO:0000313|Proteomes:UP000017048};
RX PubMed=24884595; DOI=10.1186/1471-2164-15-323;
RA Komaki H., Ichikawa N., Hosoyama A., Takahashi-Nakaguchi A., Matsuzawa T.,
RA Suzuki K., Fujita N., Gonoi T.;
RT "Genome based analysis of type-I polyketide synthase and nonribosomal
RT peptide synthetase gene clusters in seven strains of five representative
RT Nocardia species.";
RL BMC Genomics 15:323-323(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD81648.1}.
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DR EMBL; BAFO02000005; GAD81648.1; -; Genomic_DNA.
DR AlphaFoldDB; U5E5V7; -.
DR STRING; 1824.SAMN05444423_107210; -.
DR eggNOG; COG2409; Bacteria.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000017048; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017048};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..341
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 539..682
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 706 AA; 72850 MW; F0146284A93DE3C1 CRC64;
MTRARTPRPT GGPMARLGTT MADRARWVFG AWLIALIALG AAAPSVFSSL AGAGWQANGS
ESVQVRELAQ QHFGGNSSAA VQVVVHAETA TVDSPAVAAV LDAVTAQLSG DARFGEIIAP
RPGMTVSPDG HTGILVAGAA AAPDDMVRAV DDHKQALTAL SGNGIEVYPT GASALWSDFN
KANHDAMIKA ELFSWPVTLA IMVLAFGSLV AAGLPLLLTV AGLVASAGGL VLLNQVTPIS
VWAMNFAMMF ALALGIDYAL FLVARFREAL AKTGDARSAV AETMDTAGKA VVLSGLTVLV
SLSAVLLVPA PAVRTMAVGI MLAVVFVLAA TTTLLPAALG KLGHRVDGGA LPFVTRGRPS
LFARWGAVLH ARPWPFAAAG LAVLIGLAIP VFGLKVAMPS IEVVPADAAV RQGYELVQRQ
LGVGAPGALQ IVVPAADAAE TARIAAATDG IALLTPAQPG GGGLVLMQAL PEVDPSDARM
AAILDRLRAD LPGSALVGGA PAENLDLQEA LNDYLPIIVA VVLVLGFLLL LVALRAPLIA
ALGTLVSLLS TAAAFGVATL IFQDGHGAGL LGFTPQGFLD GWGPVFFFAM IFAIAMDYTV
FLLATAKEHY ERTGDPKSAL VDGLAHSGRV IFAAAAVMVA VFFTFALAEP LPPKEMGIIL
GVAVLLDALV VRLVLLPVLL RLTGHAAWWS PRWLRRILPA VNFSHH
//
