ID U5H4C3_USTV1 Unreviewed; 1254 AA.
AC U5H4C3;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=DUF726-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MVLG_02167 {ECO:0000313|EMBL:KDE07492.1};
OS Microbotryum lychnidis-dioicae (strain p1A1 Lamole / MvSl-1064) (Anther
OS smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=683840 {ECO:0000313|EMBL:KDE07492.1};
RN [1] {ECO:0000313|Proteomes:UP000017200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p1A1 Lamole {ECO:0000313|Proteomes:UP000017200};
RA Cuomo C., Perlin M., Young S.K., Zeng Q., Gargeya S., Alvarado L.,
RA Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Howarth C., Mehta T.,
RA Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Microbotryum violaceum strain p1A1 Lamole.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KDE07492.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P1A1 Lamole {ECO:0000313|EMBL:KDE07492.1};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Butler R., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heilman E., Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P.,
RA Mehta T., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA White J., Yandava C., Wortman J., Nusbaum C., Birren B.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KDE07492.1, ECO:0000313|Proteomes:UP000017200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1A1 Lamole {ECO:0000313|EMBL:KDE07492.1}, and p1A1 Lamole
RC {ECO:0000313|Proteomes:UP000017200};
RX PubMed=26076695; DOI=10.1186/s12864-015-1660-8;
RA Perlin M.H., Amselem J., Fontanillas E., Toh S.S., Chen Z., Goldberg J.,
RA Duplessis S., Henrissat B., Young S., Zeng Q., Aguileta G., Petit E.,
RA Badouin H., Andrews J., Razeeq D., Gabaldon T., Quesneville H., Giraud T.,
RA Hood M.E., Schultz D.J., Cuomo C.A.;
RT "Sex and parasites: genomic and transcriptomic analysis of Microbotryum
RT lychnidis-dioicae, the biotrophic and plant-castrating anther smut
RT fungus.";
RL BMC Genomics 16:461-461(2015).
RN [4] {ECO:0000313|EnsemblFungi:MVLG_02167T0}
RP IDENTIFICATION.
RG EnsemblFungi;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
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DR EMBL; AEIJ01000217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GL541658; KDE07492.1; -; Genomic_DNA.
DR AlphaFoldDB; U5H4C3; -.
DR EnsemblFungi; MVLG_02167T0; MVLG_02167T0; MVLG_02167.
DR HOGENOM; CLU_001695_0_1_1; -.
DR InParanoid; U5H4C3; -.
DR OMA; AIQNMEL; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000017200; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017200};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 599..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 67..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1148..1175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1211..1254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1019
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1033..1066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1238..1254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1254 AA; 136309 MW; 7D2713038B6B36AA CRC64;
MTTKWNDLDD DDWQDMPVIH STGTSVSSLR HRDDYDDDVR APHCRNAQWS HHRILPTTVQ
RHDAWIAPSS SSASTSSSHH SNGPGPSASA STASMIAGGA GGGNATGKLI DVDSGGQAWK
EKEQLDEMDY TRLELDDDPD EDEISMRTQY LFNQDKGMTP LSQMQTTKTL LTEGQRIAYV
GLCRLVAREM VQTLVLASKG APELAPARES CKTWSNKIMG RLYRHMEVDG AEQRMIEQLA
EHGVTAEDLT PSLMSTYTVT NPEYDPEAAQ AEEEKLEQQR REHEAEQEEE RKRAQEEETR
RKKEEEEARR KAQEEEQAEA ERLEIEAEAT RQEHLRVERE GRVAREVAKL ERRASLARRD
PLAFAEEFGS PVSSPTRISR SSSAHSLRSL GSPKALSPRF SPPGSPSSRQ RAFEGAEGDI
GGALDSPTTR SRTTTADSEV NDAPSASSPP PPNLPSQTVA AGAPAIALVA PDENEAVPIE
EPSSPSLSMH QPDNFLQPMP SSLPGVTTKL STADKEITLD IRWTILCDLF LSLIADSVYD
ARSRVLLCMI ADKLGLEWID VVRFERRLTE ALEIQENVKQ KEHLEVLEER RVKGQNKRYV
MMGLATLGGG LVIGLSAGLL APVIGAGLGA ALTTVGVSGT TGFLAGAGGA AIISSGATLT
GATIGGKAMA KRTRHVKTFE FLPLHNNKRV NFLITIPGFM NGPLDDVRLP FSPLDPLMGD
VFSVLWEPEM MGDTGNALKI LSTEVLTQAG QQVLALTVMT ALMSALQWPM MLTKLSYLID
NPWSNALDRA RQAGAVLADI LINRQLGVRP VSLVGFSLGA RVIFYALVEL AKANAFGVVQ
EVYLFGATVT ASMKVWRQVR GIVAGRFVNA FAMNDWVLGY LFRATSGGLQ TVAGLRPIEH
VPDLENVDIT DILMGHMSYR TLMPNLLKYV GFKVTADHFD EPEEMELDAP DREVLTAAEE
QERLERKSRK KVLGLFSRSK KSAPTNSVPM SRAQSKDEYD DLPPRLSSSS STSVDRASSD
TGDIGVGDLT SKRANRCSLS ISTVDGSDST HDGDSPALSE PSTTAAPAVP SGFDLNKIRA
EVAQLPAGSP SSPSSSPSTP FPPHSRTRTT ESEGTDAPSP AIEIALSRPQ TDLTNLDTTL
DPRELLRRRW ADESTTPSSL DPAPPVLLED QGWGSPTTPI VRRTSLAASE PTITFANDLS
GELMSQWTMQ TPPKTVSTNG REEKVVPDPA GTPFVWGGTA GSNASTVSFR ENPW
//
