ID U5HBE5_USTV1 Unreviewed; 766 AA.
AC U5HBE5;
DT 11-DEC-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Glycoside hydrolase family 5 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MVLG_04497 {ECO:0000313|EMBL:KDE05055.1};
OS Microbotryum lychnidis-dioicae (strain p1A1 Lamole / MvSl-1064) (Anther
OS smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Microbotryales; Microbotryaceae; Microbotryum.
OX NCBI_TaxID=683840 {ECO:0000313|EMBL:KDE05055.1};
RN [1] {ECO:0000313|Proteomes:UP000017200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p1A1 Lamole {ECO:0000313|Proteomes:UP000017200};
RA Cuomo C., Perlin M., Young S.K., Zeng Q., Gargeya S., Alvarado L.,
RA Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Howarth C., Mehta T.,
RA Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Microbotryum violaceum strain p1A1 Lamole.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KDE05055.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P1A1 Lamole {ECO:0000313|EMBL:KDE05055.1};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Butler R., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heilman E., Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P.,
RA Mehta T., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA White J., Yandava C., Wortman J., Nusbaum C., Birren B.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KDE05055.1, ECO:0000313|Proteomes:UP000017200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p1A1 Lamole {ECO:0000313|Proteomes:UP000017200}, and P1A1
RC Lamole {ECO:0000313|EMBL:KDE05055.1};
RX PubMed=26076695; DOI=10.1186/s12864-015-1660-8;
RA Perlin M.H., Amselem J., Fontanillas E., Toh S.S., Chen Z., Goldberg J.,
RA Duplessis S., Henrissat B., Young S., Zeng Q., Aguileta G., Petit E.,
RA Badouin H., Andrews J., Razeeq D., Gabaldon T., Quesneville H., Giraud T.,
RA Hood M.E., Schultz D.J., Cuomo C.A.;
RT "Sex and parasites: genomic and transcriptomic analysis of Microbotryum
RT lychnidis-dioicae, the biotrophic and plant-castrating anther smut
RT fungus.";
RL BMC Genomics 16:461-461(2015).
RN [4] {ECO:0000313|EnsemblFungi:MVLG_04497T0}
RP IDENTIFICATION.
RG EnsemblFungi;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEIJ01000447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GL541693; KDE05055.1; -; Genomic_DNA.
DR EMBL; GL541693; KDE05056.1; -; Genomic_DNA.
DR AlphaFoldDB; U5HBE5; -.
DR STRING; 683840.U5HBE5; -.
DR EnsemblFungi; MVLG_04497T0; MVLG_04497T0; MVLG_04497.
DR EnsemblFungi; MVLG_04497T1; MVLG_04497T1; MVLG_04497.
DR HOGENOM; CLU_009024_1_0_1; -.
DR InParanoid; U5HBE5; -.
DR OMA; NEFIPPW; -.
DR OrthoDB; 69117at2759; -.
DR Proteomes; UP000017200; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF1; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017200};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 742..760
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..166
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 621..733
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
FT REGION 656..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 766 AA; 86145 MW; 43F42536EEC9F960 CRC64;
MSDPPPAYSA AVEASHASCS AEYVIGSSSS TAASWTDSEL RMVSSSRHFH DQFDRRLLLH
GCNLSGINKL PSKPDGATHV LNEGWWDHEN VSFVGRPFPL DEAHDHLARL SQWGLTFVRF
VVTWEALEHS GPGQYDTDYI DYLRSLISLF PEYGIKCYID AHQDVWSRHT GGSGAPTWTL
ELVGFDIRNL KATGAAHAHN LNLDDDDPAP QNWPSGYTKL AGATMATLFW AGETFAPKRQ
VKRGQSAAVW GQDAPDEKVG VQVFMQKCMI GAFGALADAL TNLPAVIGFE VMNEPHPGYI
GLHSPYSFNL KKDLAIGHFP TAVQSWALGA GHSVLIDHYG PSFPVTAVTH QTLISPPKGI
TAWKEGVECV WKEQGVWAWD EQKKEALALR IEYFNQHPET GIQTDWAKDF YFPFCRDFGE
RIKEANPRWY TMAEPLPNEP CPRWTPESQP HNLIYAPHWY DLQALFTKSL GFMTANVQGL
ARGMFLLRAL YFGRNGTRKN YTAQIREVIQ SGYRTLGELP IILGETGVPF DLNGKQAFAS
GDFSWQERQM DAICSALERN LISFNLWNYN PLNTDQWGDS WNAENFSWFS QSDMTRVKFD
AAKSEDERLN VGARVLDAIE RPYASKVAGI PYAFSYDFKL LQCTFSYVNP TNPKDFRTRR
PQNLATTDDP PIPGTMPRSR ETEIYLPRRR FGGLNSRLKV RLSDGEWKYD EELQTLYVLH
ANLTPGFIHT VRISVDGEVL DALLIIAGMI VLGITMTCAL SQYDQE
//
