ID U5J9P6_9CAUD Unreviewed; 175 AA.
AC U5J9P6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=dihydrofolate reductase {ECO:0000256|ARBA:ARBA00012856};
DE EC=1.5.1.3 {ECO:0000256|ARBA:ARBA00012856};
OS Bacillus phage vB_BanS-Tsamsa.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX NCBI_TaxID=1308863 {ECO:0000313|EMBL:AGI11806.1, ECO:0000313|Proteomes:UP000017661};
RN [1] {ECO:0000313|EMBL:AGI11806.1, ECO:0000313|Proteomes:UP000017661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24475065;
RA Ganz H.H., Law C., Schmuki M., Eichenseher F., Calendar R., Loessner M.J.,
RA Getz W.M., Korlach J., Beyer W., Klumpp J.;
RT "Novel Giant Siphovirus from Bacillus anthracis Features Unusual Genome
RT Characteristics.";
RL PLoS ONE 9:E85972-E85972(2014).
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DR EMBL; KC481682; AGI11806.1; -; Genomic_DNA.
DR RefSeq; YP_008873442.1; NC_023007.1.
DR GeneID; 17825330; -.
DR KEGG; vg:17825330; -.
DR OrthoDB; 9577at10239; -.
DR Proteomes; UP000017661; Genome.
DR GO; GO:0004146; F:dihydrofolate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR CDD; cd00209; DHFR; 1.
DR Gene3D; 3.40.430.10; Dihydrofolate Reductase, subunit A; 1.
DR InterPro; IPR012259; DHFR.
DR InterPro; IPR024072; DHFR-like_dom_sf.
DR InterPro; IPR001796; DHFR_dom.
DR PANTHER; PTHR48069; DIHYDROFOLATE REDUCTASE; 1.
DR PANTHER; PTHR48069:SF3; DIHYDROFOLATE REDUCTASE; 1.
DR Pfam; PF00186; DHFR_1; 1.
DR PIRSF; PIRSF000194; DHFR; 1.
DR PRINTS; PR00070; DHFR.
DR SUPFAM; SSF53597; Dihydrofolate reductase-like; 1.
DR PROSITE; PS51330; DHFR_2; 1.
PE 4: Predicted;
FT DOMAIN 1..163
FT /note="DHFR"
FT /evidence="ECO:0000259|PROSITE:PS51330"
SQ SEQUENCE 175 AA; 20246 MW; D85C4FA8F7F07BE2 CRC64;
MISLIACVDM GMGIADKEGN LLFDLPADLR YFRETTKKQI VVMGRKTWES LPEDKRPLDR
RENYVLTRDK DFVAEGATVI HSIEEILELG KGKKEVFIMG GGELYKQMMP HADKMYVTHV
HNLNIDARVF FPNFGVEWKA LTEIKHKADK KHAHSFTFAT YKRREEEVVE AETNN
//
