ID U5LBC4_9BACI Unreviewed; 320 AA.
AC U5LBC4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU000716};
GN ORFNames=N288_13905 {ECO:0000313|EMBL:AGX04683.1};
OS Bacillus infantis NRRL B-14911.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1367477 {ECO:0000313|EMBL:AGX04683.1, ECO:0000313|Proteomes:UP000017805};
RN [1] {ECO:0000313|EMBL:AGX04683.1, ECO:0000313|Proteomes:UP000017805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-14911 {ECO:0000313|EMBL:AGX04683.1,
RC ECO:0000313|Proteomes:UP000017805};
RA Massilamany C., Smith T.P.L., Loy J.D., Barletta R., Reddy J.;
RT "Complete genome sequence of Bacillus infantis NRRL B-14911 that has
RT potential to induce cardiac disease by antigenic mimicry.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641, ECO:0000256|RuleBase:RU000716}.
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DR EMBL; CP006643; AGX04683.1; -; Genomic_DNA.
DR RefSeq; WP_022543945.1; NC_022524.1.
DR AlphaFoldDB; U5LBC4; -.
DR STRING; 1367477.N288_13905; -.
DR GeneID; 85552597; -.
DR KEGG; bif:N288_13905; -.
DR PATRIC; fig|1367477.3.peg.2733; -.
DR HOGENOM; CLU_078246_0_0_9; -.
DR Proteomes; UP000017805; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR039425; RNA_pol_sigma-70-like.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000838; RNA_pol_sigma70_ECF_CS.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR43133:SF46; ECF RNA POLYMERASE SIGMA FACTOR SIGG; 1.
DR PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS01063; SIGMA70_ECF; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000716};
KW Reference proteome {ECO:0000313|Proteomes:UP000017805};
KW Sigma factor {ECO:0000256|RuleBase:RU000716};
KW Transcription {ECO:0000256|RuleBase:RU000716};
KW Transcription regulation {ECO:0000256|RuleBase:RU000716}.
FT DOMAIN 25..90
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 119..166
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
SQ SEQUENCE 320 AA; 36152 MW; 52E58B1E37CAA65B CRC64;
MEKHNDLSSI SKDMKELAPS FDCIVQPYRE QLWHYCRKLT GSPWDAEDLL QDTLLKAFSS
LSRIGQTMNA KSYLFRIATN IWIDHCRKKS PQLLDMESEK IPDGDLVPYS EVLESVEILI
HQLPAKQAAA ILLAEVYRFT IRETAEMIGS TEGGVQSLLS RARANLKKQK AVENLPFQEA
VLADEKKQVI QQYMDYFVKG DFKSIGELLG KYATNEVVGQ GMDIGKTQIR KNSMGDWGSS
TAGLSAELAF LWGRYAVIYT RDAGCGPVLW DIATAEIEDG KLIRHKSYYF CREFLEAAAA
ELSIKLDTEK DLFGQEWQGI
//
