ID   U5MQ37_CLOSA            Unreviewed;       320 AA.
AC   U5MQ37;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Ketopantoate reductase {ECO:0000313|EMBL:AGX42705.1};
DE            EC=1.1.1.169 {ECO:0000313|EMBL:AGX42705.1};
GN   ORFNames=CLSA_c17100 {ECO:0000313|EMBL:AGX42705.1};
OS   Clostridium saccharobutylicum DSM 13864.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1345695 {ECO:0000313|EMBL:AGX42705.1, ECO:0000313|Proteomes:UP000017118};
RN   [1] {ECO:0000313|EMBL:AGX42705.1, ECO:0000313|Proteomes:UP000017118}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13864 {ECO:0000313|EMBL:AGX42705.1};
RX   PubMed=24285650;
RA   Poehlein A., Hartwich K., Krabben P., Ehrenreich A., Liebl W., Durre P.,
RA   Gottschalk G., Daniel R.;
RT   "Complete Genome Sequence of the Solvent Producer Clostridium
RT   saccharobutylicum NCP262 (DSM 13864).";
RL   Genome Announc. 1:e00997-13(2013).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP006721; AGX42705.1; -; Genomic_DNA.
DR   RefSeq; WP_022745272.1; NZ_AYXL01000329.1.
DR   AlphaFoldDB; U5MQ37; -.
DR   GeneID; 55474198; -.
DR   KEGG; csb:CLSA_c17100; -.
DR   PATRIC; fig|1345695.10.peg.3833; -.
DR   eggNOG; COG1893; Bacteria.
DR   HOGENOM; CLU_055593_0_0_9; -.
DR   OrthoDB; 9793586at2; -.
DR   Proteomes; UP000017118; Chromosome.
DR   GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF02558; ApbA; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:AGX42705.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017118}.
FT   DOMAIN          3..156
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
SQ   SEQUENCE   320 AA;  36606 MW;  F8791AB6EF3F0F6D CRC64;
     MKILIYGAGV LGSYATYELK RVGHEVTILA RGKRYEELKE KGLVIRHWLQ RRTTVDKINI
     VKELLPEDQY DVTFIVMQSS QVKAVLPDIS ANVRCPLFVF VGNEDKAKEI ADEIKNTSIS
     NPRILFGFFS IGGRREDGKV ISVHTKHPDF DIGNLEGKDD YKSILEKIFK ATRFKIKYHI
     NMDDFFKTHI AFIMPLAYLA YMSNCDLRKI ASNKKALNAA IDAIVEGCDV LVKLGYKIDP
     EISLNFLKNY RKIVYFGLKL CVATPVGRLA ISDHCKAACN EMKYLDKTLV ELTKKSKLQT
     PNINKLREYL IKYVNQKNIQ
//