ID U5P5V4_9STRE Unreviewed; 690 AA.
AC U5P5V4;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Collagen-binding protein {ECO:0000313|EMBL:AGY38870.1};
GN ORFNames=N597_07840 {ECO:0000313|EMBL:AGY38870.1};
OS Streptococcus ilei.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1156431 {ECO:0000313|EMBL:AGY38870.1, ECO:0000313|Proteomes:UP000017124};
RN [1] {ECO:0000313|EMBL:AGY38870.1, ECO:0000313|Proteomes:UP000017124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I-P16 {ECO:0000313|Proteomes:UP000017124};
RA Hyun D.-W.;
RT "Genome sequence of Streptococcus SP. I-P16 isolated from human ileal
RT fluid.";
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
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DR EMBL; CP006776; AGY38870.1; -; Genomic_DNA.
DR RefSeq; WP_023024420.1; NC_022582.1.
DR AlphaFoldDB; U5P5V4; -.
DR STRING; 1156433.N597_07840; -.
DR KEGG; sip:N597_07840; -.
DR PATRIC; fig|1156433.3.peg.1546; -.
DR HOGENOM; CLU_002287_4_1_9; -.
DR Proteomes; UP000017124; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005518; F:collagen binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00222; CollagenBindB; 2.
DR Gene3D; 2.60.40.1280; -; 1.
DR Gene3D; 2.60.40.740; -; 1.
DR Gene3D; 2.60.40.1140; Collagen-binding surface protein Cna, B-type domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR008454; Collagen-bd_Cna-like_B-typ_dom.
DR InterPro; IPR008456; Collagen-bd_dom.
DR InterPro; IPR011252; Fibrogen-bd_dom1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR041171; SDR_Ig.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR Pfam; PF17961; Big_8; 1.
DR Pfam; PF05738; Cna_B; 2.
DR Pfam; PF05737; Collagen_bind; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17802; SpaA; 1.
DR SUPFAM; SSF49401; Bacterial adhesins; 2.
DR SUPFAM; SSF49478; Cna protein B-type domain; 3.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Collagen {ECO:0000313|EMBL:AGY38870.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..690
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039492345"
FT TRANSMEM 662..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 656..690
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 606..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..631
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..646
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 74638 MW; 19E58A9DCC416348 CRC64;
MKKWLYAVVT TVALFLLAAL GFAKPNGVTK AHADTINDVV SSVNISKATG GDLTEPLGVW
ESFNVEANFV LPNGRVKAGD QTVIQLGDGF KVFETDTIDL LDPTGQKVAT ATVDDQRKVI
TVTYTDYPEK MANVTGKLRF FARVDHSVIK GNTTLDFTLS VDKTVISGGK VDYKGVNPGE
YPPTPEVFSK WGWTNSGDKL KLTYTLNINQ GHTALHNIDI KDQLAFTDGK IKVDSVNIHT
GTWKISDEDG AYHLGDTTNV TSHYSPVVSE DGRSLTVHIG DLAPEQGMTI RYDVYLDKVP
AINTEYKNNA TMTATEVKEQ HKEADILYQF FEGAFNGEKY SFTIHKKGEN GQALAGAVFT
VTADDTGEQV GTITTDEKGT GTVAGLIKQA YTVQEIQAPT GYVLSEEPIK ISKEDFGNDL
AISREVINKK EKTSISGQKT WNDNDNHDGK RPSAITINLL ANGVKVASKE VKPDAEGNWL
YQFDNLDVVD DTGNLIAYTV SEEPVAGYET SVEGTNITNS RTPEVTEVAV KKVWDDKENK
DGLRPDKVTV RLLADGQEVA VKEITATDNW QASFTDLPVY KEGKKIVYTI TEDPVAGYTA
TIDGFTVTNR HTPPTTPPPS TTTPPPASTT PSTTTPSTSE KPGTPTTPTE GKRKILPSTG
EATSYGLFGA SALLALVGAA MLLSGKRKAD
//
