ID U5Q848_9BACT Unreviewed; 497 AA.
AC U5Q848;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=resE {ECO:0000313|EMBL:AGY54628.1};
GN ORFNames=BRDCF_p2001 {ECO:0000313|EMBL:AGY54628.1};
OS Bacteroidales bacterium CF.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX NCBI_TaxID=1400053 {ECO:0000313|EMBL:AGY54628.1, ECO:0000313|Proteomes:UP000017642};
RN [1] {ECO:0000313|EMBL:AGY54628.1, ECO:0000313|Proteomes:UP000017642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AGY54628.1};
RX PubMed=24356833;
RA Tang S., Edwards E.A.;
RT "Complete Genome Sequence of Bacteroidales Strain CF from a Chloroform-
RT Dechlorinating Enrichment Culture.";
RL Genome Announc. 1:e01066-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP006772; AGY54628.1; -; Genomic_DNA.
DR AlphaFoldDB; U5Q848; -.
DR STRING; 1400053.BRDCF_p2001; -.
DR KEGG; bacc:BRDCF_p2001; -.
DR HOGENOM; CLU_548203_0_0_10; -.
DR OrthoDB; 9781208at2; -.
DR Proteomes; UP000017642; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGY54628.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000017642};
KW Transferase {ECO:0000313|EMBL:AGY54628.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..495
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 497 AA; 55879 MW; E9BFFE7BAA98FFAD CRC64;
MAMNIKRLFG VFFTIIIILL TGMGVISILI LNTQKDGYSN QDARVQVWAA ASELRVSSEN
LTQYARAYVS TRDSAWLYKY YDALEKRSGK IPRENGRAIS LLDSIAKIKI PEAEFALLKE
SEHRSNDLSI VEIAAMNAAR GLYPDKTLKY TVKGKVDLEY ANDLLYSDKY RSDKKLVMDP
IDEFLSLLKK RAISSVDYYN SKITYYTTIE LTLAILVGLF SLASFIILRG RLIKKMEECN
TSNIRLKEAE SVLKIQNEEL DKLNASKDKF FSIIAHDLRG PVGILMNFAE LLEEKIKEKD
YTDIEVFTKN LSQSSISVNE LLNNLLNWAR AQNPNIKASI SEFDPMPVIR KNIELCAMLA
REKDIEMTLE NTDNLLVIAD PDQISLVFRN ILWNAIKFTP KNGKISINVT GMNAGGKYIA
KISFTDTGVG MNQSQVEKLF RIDSISTTRG TAGEHGTGLG LILCKDYIEL NQGKITVDSR
LNTGTTFTVY LPSKTVA
//
