ID   U5RSB1_9CLOT            Unreviewed;       328 AA.
AC   U5RSB1;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Tyrosine recombinase XerC {ECO:0000313|EMBL:AGY74419.1};
GN   ORFNames=CAETHG_0186 {ECO:0000313|EMBL:AGY74419.1};
OS   Clostridium autoethanogenum DSM 10061.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1341692 {ECO:0000313|EMBL:AGY74419.1, ECO:0000313|Proteomes:UP000017590};
RN   [1] {ECO:0000313|EMBL:AGY74419.1, ECO:0000313|Proteomes:UP000017590}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10061 {ECO:0000313|EMBL:AGY74419.1};
RX   PubMed=24655715; DOI=10.1186/1754-6834-7-40;
RA   Brown S.D., Nagaraju S., Utturkar S., De Tissera S., Segovia S.,
RA   Mitchell W., Land M.L., Dassanayake A., Kopke M.;
RT   "Comparison of single-molecule sequencing and hybrid approaches for
RT   finishing the genome of Clostridium autoethanogenum and analysis of CRISPR
RT   systems in industrial relevant Clostridia.";
RL   Biotechnol. Biofuels 7:40-40(2014).
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000256|ARBA:ARBA00003283}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
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DR   EMBL; CP006763; AGY74419.1; -; Genomic_DNA.
DR   RefSeq; WP_013238751.1; NZ_CP012395.1.
DR   AlphaFoldDB; U5RSB1; -.
DR   KEGG; cah:CAETHG_0186; -.
DR   PATRIC; fig|1341692.11.peg.179; -.
DR   HOGENOM; CLU_027562_9_6_9; -.
DR   Proteomes; UP000017590; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   PANTHER; PTHR30349:SF41; INTEGRASE_RECOMBINASE HI_1414-RELATED; 1.
DR   PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01248}.
FT   DOMAIN          11..116
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000259|PROSITE:PS51900"
FT   DOMAIN          138..319
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
SQ   SEQUENCE   328 AA;  38296 MW;  2D7A311E7E615762 CRC64;
     MQYNLSNIYN PELPQCLNDF LNYLGTIRGK SKNTQDGYQV DLTMFFRFLK IYRGIVKENY
     EFENIDISDI NTDFIRKITL SDLYAFISFA ENYRNNGNYA RARKVACLKS FFKYLFSKAK
     LIDTNPALEL ESPKIDKRNP IYLSLKESKI LLNSIDGKFK ERDYCIITFF LNCGMRLSEL
     CSINISKIKE DTLTVVGKGN KERTIYLNRA CLTALNNYLE IRNKDYDKIK DKDALFLSKN
     HTRINKRSVE MMLKKYLKNA GLDSNKYTPH KLRHTAATLM YKYGNVDIRS LQKILGHENV
     STTQIYTHVD DEQLREAVNS NPLSNEEE
//