ID U5RTU5_9CLOT Unreviewed; 641 AA.
AC U5RTU5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Sigma-54-dependent Fis family transcriptional regulator {ECO:0000313|EMBL:AGY74783.1};
GN ORFNames=CAETHG_0554 {ECO:0000313|EMBL:AGY74783.1};
OS Clostridium autoethanogenum DSM 10061.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1341692 {ECO:0000313|EMBL:AGY74783.1, ECO:0000313|Proteomes:UP000017590};
RN [1] {ECO:0000313|EMBL:AGY74783.1, ECO:0000313|Proteomes:UP000017590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10061 {ECO:0000313|EMBL:AGY74783.1};
RX PubMed=24655715; DOI=10.1186/1754-6834-7-40;
RA Brown S.D., Nagaraju S., Utturkar S., De Tissera S., Segovia S.,
RA Mitchell W., Land M.L., Dassanayake A., Kopke M.;
RT "Comparison of single-molecule sequencing and hybrid approaches for
RT finishing the genome of Clostridium autoethanogenum and analysis of CRISPR
RT systems in industrial relevant Clostridia.";
RL Biotechnol. Biofuels 7:40-40(2014).
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DR EMBL; CP006763; AGY74783.1; -; Genomic_DNA.
DR RefSeq; WP_023161878.1; NC_022592.1.
DR AlphaFoldDB; U5RTU5; -.
DR KEGG; cah:CAETHG_0554; -.
DR PATRIC; fig|1341692.4.peg.560; -.
DR HOGENOM; CLU_000445_8_12_9; -.
DR Proteomes; UP000017590; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF119; SIGMA-54 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 197..249
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 324..554
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 641 AA; 72480 MW; 34197A4DE89866F8 CRC64;
MFKPFTHSEI VSRSLNRCIK YHIEKGIPKP KRTLSRKELD NLIKENNDII KIAKPFMEIL
YDFLSGSGFS LYLTDKNGIV LTIIGDKDIV MEQAKAGIAE GIDLSEQSAG TNAAGTAIFE
NLSVQLSGKE HFINTFQIYT CSASVIHNEQ GNIIGCLTLT GKRQLAHPHT LGLVVSAVKS
IENHLKLNKS QNELFKAYQY LNKIMNSMDF GIFAVDNSGI VKAINNSACN LLGINQKDII
DKNVYKVLHI WQYILDELKS GNVYTDKEIL YSDEKKRFNL NVYPIKDKSN IVTGMVVIFK
DIQNVYNLVN KYTSGSAAYT FDDIIGNSEK MINLKEQLKN ISNSPSTVLI QGESGTGKEL
IAQSIHNDSN RKNKSFIAIN CGAIPKNLIE SELFGYEDGS FTGAKRGGRA GKFELANGGT
LFLDEIGEMP LDMQVNLLRV LQENCITRIG GNKCIKIDVR IIAATNKNLR EKIKKGTFRE
DLYYRLNVIP IYVPPLRERD MDIKILIDYF LKIKAFKLKK PIPIVRPDIY QKLLKHNWPG
NVRELENCIE NIVNMNGNTS FDFQNNLSVN KQTNPCTTNL KYDMCSLEEW EKKAIINCIH
NCNHNMSKAS KILGINRSTL YTKIKNIKLI FLKLYIKTTL L
//
