ID   U5RUS3_9CLOT            Unreviewed;      1361 AA.
AC   U5RUS3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=AAA domain-containing protein {ECO:0000313|EMBL:AGY76506.1};
GN   ORFNames=CAETHG_2295 {ECO:0000313|EMBL:AGY76506.1};
OS   Clostridium autoethanogenum DSM 10061.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1341692 {ECO:0000313|EMBL:AGY76506.1, ECO:0000313|Proteomes:UP000017590};
RN   [1] {ECO:0000313|EMBL:AGY76506.1, ECO:0000313|Proteomes:UP000017590}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10061 {ECO:0000313|EMBL:AGY76506.1};
RX   PubMed=24655715; DOI=10.1186/1754-6834-7-40;
RA   Brown S.D., Nagaraju S., Utturkar S., De Tissera S., Segovia S.,
RA   Mitchell W., Land M.L., Dassanayake A., Kopke M.;
RT   "Comparison of single-molecule sequencing and hybrid approaches for
RT   finishing the genome of Clostridium autoethanogenum and analysis of CRISPR
RT   systems in industrial relevant Clostridia.";
RL   Biotechnol. Biofuels 7:40-40(2014).
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DR   EMBL; CP006763; AGY76506.1; -; Genomic_DNA.
DR   RefSeq; WP_013236882.1; NZ_CP012395.1.
DR   KEGG; cah:CAETHG_2295; -.
DR   PATRIC; fig|1341692.11.peg.2317; -.
DR   HOGENOM; CLU_000738_1_0_9; -.
DR   Proteomes; UP000017590; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF18741; MTES_1575; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          274..410
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          1023..1205
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   DOMAIN          1248..1340
FT                   /note="Restriction endonuclease type II-like"
FT                   /evidence="ECO:0000259|Pfam:PF18741"
SQ   SEQUENCE   1361 AA;  159736 MW;  578282C98CA6F82D CRC64;
     MEYREKIKEI FSYLLRLKKL NEKSVRNVYD YDKLYWEEEF SHMAGCIVSK TVTSENWIEV
     NKKCGKLYQE FFNLYQESEK NGENFEIVFG HGLIVWNIDK EKILHPVLTT RMKIEFNKAK
     GSFILIPSGK TRLETSIFEG LKECNMSDII SLGDEVSRLN LDPRNIEKSK SVFLNLISHI
     NVKGKLSQSK VLKKKIDFEQ FPVIYNSSVI LVRKNSMKLW QVEIANIIDE IDNGYEIPET
     IKALVDEDGS DYSGADKSEW KDVSDNLLFP LPANSEQKSI VKKICENYGV VVQGPPGTGK
     SHTIVNLICH LLANGKKILV TSQTSRALKV LTEKIPEEIR PLCISVLGND INSLNDLNKA
     VRKITDNLSM DPEIMDEEVK SLEKELSFCR RNEELLYEKL KKIREREKRS INYEGKEYDI
     VYIAKWVKDN KDKYSWMKDR IKIDQVMPLS DKEFNLLIYL LGDLDKDKKC KFDSIKNIIN
     KLPDFNEIYN KISEYKRLNG QYENYIKTVE GWHIPNDNKC NYEKVLELAN ICKSKITKLQ
     EKNIWWNVFQ DYHNSKISKQ TFRDLLCKSS EYMLSLSRIN NQIRNCKIEI PENVSKNKFI
     EDFDILFDAF NEKGKVGKVF MIFHPECKYI LEYCKVNGAL LKNTDQALIV KLYTQQERIF
     AALKTMWNNV MEDYGGETIN SNLRESEFIA IEQNLNYLDV IINWDMEYKR EILRALGKIS
     VPQNIDWHKK ETYDYLIKCV NFIKNMNKYN EDKAYIEILK KLIKTTEKLR DLYKAVDNLN
     IDEVKRILNE FEEIKCVKNK SLKIDELIGK MKKVCPKTCI NILDNWAYDK EKFNSWGQAW
     KWAKWNSLLQ STYDFNDDNI GDLIENEKNR EKVLIKDIVS KKTWYNQIIK TKESEKRSLF
     SWAQAVKRIG KGRGKMVPQY RKIAQKEMEK CKKVIPVWIM PLNRVIENIK LSKNMFDVII
     FDESSQSDIF SLCALMRAKR AVIVGDDKQI SPETIGIDQN VVHDLIEKYL ENIPQKEWFD
     LQVSLYDTAL RVFPSRLMLK EHFRCVPEII NFSNDLSYSG EIVPLRYPKI CEKFYPAINT
     VKVNGGARDA SKPINVKEAE CLVDKVVSCC RDKRYSNMSM GVISLLGEPQ GHLIENMLRE
     KIGVEEMINR KLICGDAYSF QGDERDIMFL SMVISKDVKF APLTKENDIR RFNVAASRAR
     NQMWLFHSID LEDLNEECVR YSLLNYFLNY NKYSVKNKSM EYAFQSRFQK DVYGIIKNKG
     YKIVPEVKIG KYKIDFVVED VRNRVAIICD SELSQKNYSS KEIMEIQLDL ERLGWIFYKI
     REGEFYYNPE RVMEKLWSKL NNIGIEQYKL EEIQNKNLQV V
//