ID U5TG18_COWPX Unreviewed; 378 AA.
AC U5TG18;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 03-MAY-2023, entry version 25.
DE SubName: Full=CPXV217 protein {ECO:0000313|EMBL:AGY99855.1};
GN Name=CPXV217 {ECO:0000313|EMBL:AGY99855.1};
OS Cowpox virus (CPV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10243 {ECO:0000313|EMBL:AGY99855.1, ECO:0000313|Proteomes:UP000173670};
OH NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH NCBI_TaxID=10090; Mus musculus (Mouse).
OH NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN [1] {ECO:0000313|Proteomes:UP000097445, ECO:0000313|Proteomes:UP000115255}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EleGri07/1 {ECO:0000313|EMBL:AGZ00496.1}, HumGri07/1
RC {ECO:0000313|EMBL:AGZ01338.1}, HumLan08/1
RC {ECO:0000313|EMBL:AGY97288.1}, JagKre08/1
RC {ECO:0000313|EMBL:AGY98361.1}, JagKre08/2
RC {ECO:0000313|EMBL:AGY98578.1}, MonKre08/4
RC {ECO:0000313|EMBL:AGY99014.1}, and RatHei09/1
RC {ECO:0000313|EMBL:AGY99855.1};
RA Dabrowski P.W., Radonic A., Kurth A., Nitsche A.;
RT "Genome-wide comparison of cowpoxviruses reveals a new clade related to
RT Variola virus.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the serpin family. Poxviruses subfamily.
CC {ECO:0000256|ARBA:ARBA00008009}.
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DR EMBL; KC813492; AGY97288.1; -; Genomic_DNA.
DR EMBL; KC813497; AGY98361.1; -; Genomic_DNA.
DR EMBL; KC813498; AGY98578.1; -; Genomic_DNA.
DR EMBL; KC813500; AGY99014.1; -; Genomic_DNA.
DR EMBL; KC813504; AGY99855.1; -; Genomic_DNA.
DR EMBL; KC813507; AGZ00496.1; -; Genomic_DNA.
DR EMBL; KC813511; AGZ01338.1; -; Genomic_DNA.
DR Proteomes; UP000097445; Genome.
DR Proteomes; UP000115255; Genome.
DR Proteomes; UP000131496; Genome.
DR Proteomes; UP000137723; Genome.
DR Proteomes; UP000163863; Genome.
DR Proteomes; UP000172256; Genome.
DR Proteomes; UP000173670; Genome.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19583; serpinN_SPI-1_SPI-2; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF211; ACCESSORY GLAND PROTEIN ACP76A-RELATED; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
FT DOMAIN 18..377
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 378 AA; 43768 MW; EE2E27975BA9E3C0 CRC64;
MNIYYISFRY RYYLVYAMDI FKELILKHTD ENVLISPVSI LSTLSILNHG AAGSTAEQLS
KYIENVNENE NENASEDKKD DNNDMDVDIP YCATLATANK IYCSDSIEFH ASFLQKIKDD
FQTVNFNNAN QTKELINEWV KTMTNGKINV LLTSPLPINT RMTIVSAVHF KAMWKYPFSK
HLTYTDKFYI SKNIVSSVDM MVSTENDLQY VHINELFGGF SIIDIPYEGN SSMVIILPDD
IEGIYNIEKN ITDEKFKKWC GMLSTKSIDL YMPKFKLEMT EPYNLVPILE NLGLTNIFGY
YADFSKMCNE TITVEKFLHK TFIDVNEEYT EASAITGVFM TNFSMVYRTK VYINHPFIYM
IKDNTGRILF IGKYCYPQ
//
