ID   U5VPJ9_9ACTN            Unreviewed;       368 AA.
AC   U5VPJ9;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=citrate synthase (unknown stereospecificity) {ECO:0000256|ARBA:ARBA00012972};
DE            EC=2.3.3.16 {ECO:0000256|ARBA:ARBA00012972};
GN   ORFNames=AFR_02200 {ECO:0000313|EMBL:AGZ38729.1};
OS   Actinoplanes friuliensis DSM 7358.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1246995 {ECO:0000313|EMBL:AGZ38729.1, ECO:0000313|Proteomes:UP000017746};
RN   [1] {ECO:0000313|EMBL:AGZ38729.1, ECO:0000313|Proteomes:UP000017746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7358 {ECO:0000313|EMBL:AGZ38729.1,
RC   ECO:0000313|Proteomes:UP000017746};
RX   PubMed=24637369; DOI=10.1016/j.jbiotec.2014.03.011;
RA   Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Fischer N.,
RA   Steinkamper A., Puhler A., Biener R., Schwartz D., Kalinowski J.;
RT   "Complete genome sequence of the actinobacterium Actinoplanes friuliensis
RT   HAG 010964, producer of the lipopeptide antibiotic friulimycin.";
RL   J. Biotechnol. 178:41-42(2014).
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC       {ECO:0000256|ARBA:ARBA00005163}.
CC   -!- SIMILARITY: Belongs to the citrate synthase family.
CC       {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU003406}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP006272; AGZ38729.1; -; Genomic_DNA.
DR   RefSeq; WP_023357672.1; NC_022657.1.
DR   AlphaFoldDB; U5VPJ9; -.
DR   STRING; 1246995.AFR_02200; -.
DR   KEGG; afs:AFR_02200; -.
DR   PATRIC; fig|1246995.3.peg.445; -.
DR   eggNOG; COG0372; Bacteria.
DR   HOGENOM; CLU_025068_2_1_11; -.
DR   OrthoDB; 9800864at2; -.
DR   UniPathway; UPA00223; -.
DR   Proteomes; UP000017746; Chromosome.
DR   GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR   Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR   InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR   InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR   InterPro; IPR002020; Citrate_synthase.
DR   InterPro; IPR019810; Citrate_synthase_AS.
DR   InterPro; IPR036969; Citrate_synthase_sf.
DR   PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR   PANTHER; PTHR11739:SF23; CITRATE SYNTHASE 2-RELATED; 1.
DR   Pfam; PF00285; Citrate_synt; 1.
DR   PRINTS; PR00143; CITRTSNTHASE.
DR   SUPFAM; SSF48256; Citrate synthase; 1.
DR   PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:AGZ38729.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017746};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003406}.
SQ   SEQUENCE   368 AA;  39896 MW;  69FAE7E29CE197C0 CRC64;
     MSDFKPGLEG VIAFETEIAE PDKAGGSLRY RGVDIEDLIG QVSFGNVWAL LVDGRFGPGL
     PPAEPFPVPV HSGDIRVDVQ SAVAMLAPYW GLDQMLDIDE DQTRADLARV SVTALSFVAQ
     AARGLGLPAV PQKDIDKAQT IVERFMKRWR GEPDPRHVKA VDAYFISAAE HGLNASTFTT
     RIVASTGADA AACISAGIGA LSGPLHGGAP SRVLHMIEAV ERSGDAEGYV KGVLDRGERL
     MGFGHRVYRA EDPRARVLRR TAKELGAPRF EVAEALEKAA LAELQARKPD RVLMTNVEFW
     SAVVLDFAEV PAHMFTSMFT CARVAGWSAH ILEQKKLGRI VRPSALYVGP DTRKPQDVEG
     WDAVPHNL
//